Bus Tickets from Rome to Brussels

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MonJun 23
TodayJun 24
from US$70
TomorrowJun 25
ThuJun 26
FriJun 27
SatJun 28
SunJun 29
MonJun 30

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 24 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: June 25 at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 24 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: June 25 at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: June 25 at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: June 25 at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: June 25 at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 7:01 PM CEST.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Rome to Brussels

Bus
Average PriceUS$68 - US$363Average Duration1d 6h
29kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average PriceUS$152 - US$153Average Duration17h 30m
49kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Rome to Brussels

Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 1 day, 6 hours 25 minutes, and with fares starting at just US$68, it presents an excellent value for a comfortable ride.

26bus per day
1d 6hAverage Duration
US$68Cheapest ticket
29kgCO₂ emissions

Bus Rome to Brussels: Trip Overview

Average Ticket PriceUS$145
Average Bus Trip Duration1d 6h
Number of daily buses25.176470588235297
Earliest bus departure12:10am
Distance1173 km
Latest bus departure11:50pm

Rome to Brussels Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rome to Brussels.

We make sure you can find a bus service from Rome to Brussels from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Rome to Brussels, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Rome - Brussels

  1. How far is Rome from Brussels?

    The distance covered from Rome to Brussels is 1175 km (729 miles).

  2. What are the departure and arrival locations for buses traveling from Rome to Brussels?

    Buses traveling this route start their trip at Rome Tiburtina Bus Station, in Rome, and end it at Brussels South (Gare du Midi), in Brussels.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-22
No data
06-23
No data
Today
US$66
06-25
No data
06-26
US$65
06-27
US$95
06-28
US$108
06-29
No data
busbud logoThe cheapest trip from Rome to Brussels was searched and found on Jun 26, 2025 with a price of US$65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels, as early as possible.

You can expect to pay from US$65 to US$230 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$65 which is on 2025-06-26.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rome to Brussels but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Brussels, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rome to Brussels that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Brussels.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Rome to Brussels?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rome by bus?

Bus from Rome to Brussels

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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