Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Brussels-South (Gare du Midi) | CheapestFastest | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags |
Last refresh of the prices: Yesterday at 11:24 CET.
Compare 2 ways to travel from Rome to Brussels
Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 15 hours and with fares starting at just £112, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£57 - £293 | Average duration1d 6h | 30kg CO₂e | ||
Carpool | Average price£112 - £112 | Average duration15h | 49kg CO₂e |
Where are the popular stops in Rome and Brussels?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about travelling by bus from Rome to Brussels
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Rome to Brussels?
The cheapest coach tickets from Rome to Brussels start from £57. The average price for this route is around £116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Rome to Brussels?
The average bus journey time from Rome to Brussels is 1d 6h, covering a distance of 733 miles. The fastest bus can take you there in 22h 30m and is operated by FlixBus.
Which bus companies service the Rome to Brussels route?
Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Rome to Brussels?
The earliest bus departs from Rome to Brussels at 00:10. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Rome to Brussels?
A bus journey from Rome to Brussels produces an estimated 30 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Rome to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1058 reviews.
Which company has the best Wi-Fi from Rome to Brussels?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Rome to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rome to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brussels was searched and found on 14 Dec 2025 with a price of £76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels as early as possible.
You can expect to pay from £76 to £105 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £76, which is on 2025-12-14.
