Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Main Station - parking) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Na Knížecí) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | PRG Airport | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Main Station - parking) | Südseite Hauptbahnhof | No tags |
Compare 3 ways to go from Prague to Karlsruhe
Among the sustainable travel choices, the carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours, and with fares starting at just $35, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Karlsruhe?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - CChlumecká, 198 00 Praha 20, Czech Republic
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
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Frequently asked questions about travelling from Prague to Karlsruhe by bus
What is the distance between Prague and Karlsruhe?
The distance between Prague and Karlsruhe is around 453 km (281 miles).
What are the departure and arrival locations for buses traveling from Prague to Karlsruhe?
Buses traveling this route start their trip at PRG Airport, in Prague, and end it at Südseite Hauptbahnhof, in Karlsruhe.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Karlsruhe was searched and found on Nov 26, 2025 with a price of $35To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Karlsruhe, as early as possible.
You can expect to pay from $35 to $55 for a bus ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-26.
