Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | PRG Airport | Südseite Hauptbahnhof | CheapestFastest | |||||
| Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | |||||
Flixbus + Flixtrain | Prague (Central Bus Station Florenc) | Karlsruhe Hbf | No tags | |||||
| Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | |||||
Flixbus + Flixtrain | Prague (Central Bus Station Florenc) | Karlsruhe Hbf | No tags |
Last refresh of the prices: Today at 9:37 AM CET.
Compare 3 ways to travel from Prague to Karlsruhe
Among the sustainable travel choices, the carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours and with fares starting at just R 426, it presents an excellent value for a comfortable ride.
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Where are the popular stops in Prague and Karlsruhe?
Frequently asked questions about travelling from Prague to Karlsruhe by bus
How much does a bus ticket from Prague to Karlsruhe cost?
The bus ticket price from Prague to Karlsruhe starts at R 483. The best way to find cheap bus tickets from Prague to Karlsruhe is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Prague to Karlsruhe?
The average travel time between Prague and Karlsruhe is around 9h 55m, although the fastest bus will take about 7h 50m. This is the time it takes to travel the 453 km that separates the two cities.
How many daily bus connections are there between Prague and Karlsruhe?
The number of buses from Prague to Karlsruhe can differ depending on the day of the week. On average, there are 18 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Prague to Karlsruhe by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Prague to Karlsruhe?
When taking the bus from Prague to Karlsruhe, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, LEX CLUB.
What are the departure and arrival stations when taking the bus from Prague to Karlsruhe?
Buses travelling between Prague and Karlsruhe leave from Zličín or Černý Most and arrive at Südseite Hauptbahnhof, Karlsruhe Hbf, Goethestraße.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Karlsruhe was searched and found on 20 Nov 2025 with a price of R 567To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Karlsruhe as early as possible.
You can expect to pay from R 567 to R 1 147 for a bus ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at R 567, which is on 2025-11-20.
