Bus Tickets from Pittsburgh to St. Louis

Find affordable bus tickets from Pittsburgh to St. Louis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 14
from US$98
TomorrowJul 15
from US$81
WedJul 16
from US$85
ThuJul 17
from US$85
FriJul 18
SatJul 19
from US$81
SunJul 20
MonJul 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: July 15 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: July 16 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: July 16 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 5:07 AM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Pittsburgh to St. Louis

Bus
Average PriceUS$79 - US$201Average Duration13h 45m
22kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$119 - US$882Average Duration23h 24m
82kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 13 hours 45 minutes, and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

3bus per day
13h 45mAverage Duration
US$79Cheapest ticket
22kgCO₂ emissions

Bus Pittsburgh to St. Louis: Trip Overview

Average Ticket PriceUS$85
Average Bus Trip Duration13h 45m
Number of daily buses3
Earliest bus departure1:35am
Distance898 km
Latest bus departure7:45pm

Pittsburgh to St. Louis Bus

Busbud helps you find a bus from Pittsburgh to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Pittsburgh to St. Louis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Pittsburgh to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Pittsburgh - St. Louis

  1. What is the travel distance from Pittsburgh to St. Louis?

    The distance between Pittsburgh and St. Louis is around 899 km (557 miles).

  2. What are the departure and arrival locations for buses traveling from Pittsburgh to St. Louis?

    Buses traveling this route start their trip at Intermodal Station, in Pittsburgh, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-12
US$87
07-13
US$108
Today
US$90
07-15
US$73
07-16
US$77
07-17
US$77
07-18
No data
07-19
US$73
busbud logoThe cheapest trip from Pittsburgh to St. Louis was searched and found on Jul 15, 2025 with a price of US$73

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St. Louis, as early as possible.

You can expect to pay from US$73 to US$144 for a bus ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$73 which is on 2025-07-15.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Pittsburgh and St. Louis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Pittsburgh to St. Louis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to St. Louis that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Pittsburgh to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Pittsburgh to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Pittsburgh to St. Louis

You can also go to St. Louis by train

Train from Pittsburgh to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Pittsburgh

Buses Leaving from Pittsburgh

Buses Going to Pittsburgh

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis