Find coaches from Pittsburgh to St. Louis

Previously seen journeys

Next departures from Pittsburgh to St. Louis on 14 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Pittsburgh Intermodal Station
Gateway StationNo tags
GreyhoundBus
Pittsburgh Intermodal Station
Gateway StationNo tags
GreyhoundBus
Pittsburgh Intermodal Station
Gateway StationNo tags
GreyhoundBus
Pittsburgh Intermodal Station
Gateway StationNo tags
GreyhoundBus
Pittsburgh Intermodal Station
Gateway StationNo tags

Compare 2 ways to travel from Pittsburgh to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 13 hours 35 minutes and with fares starting at just R 1 039, it presents an excellent value for a comfortable ride.

3bus per day
13h 35mAverage duration
899 kmDistance
22kgCO₂ emissions
Bus
Average priceR 1 039 - R 3 989Average duration13h 35m
22kg CO₂e
Train
Average priceR 1 403 - R 16 270Average duration23h 24m
82kg CO₂e

Frequently asked questions about travelling from Pittsburgh to St. Louis by bus

  1. How much does a bus ticket from Pittsburgh to St. Louis cost?

    The bus ticket price from Pittsburgh to St. Louis starts at R 1 039. The best way to find cheap bus tickets from Pittsburgh to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Pittsburgh to St. Louis?

    The average travel time between Pittsburgh and St. Louis is around 13h 35m, although the fastest bus will take about 11h 55m. This is the time it takes to travel the 899 km that separates the two cities.

  3. How many daily bus connections are there between Pittsburgh and St. Louis?

    The number of buses from Pittsburgh to St. Louis can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Pittsburgh to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Pittsburgh to St. Louis?

    When taking the bus from Pittsburgh to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Pittsburgh to St. Louis?

    Buses travelling between Pittsburgh and St. Louis leave from Intermodal Station or Sennott Square and arrive at Gateway Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/11
R 1 440
13/11
R 1 440
Today
R 1 440
15/11
R 1 071
16/11
R 1 036
17/11
R 1 001
18/11
R 1 001
19/11
R 1 098
busbud logoThe cheapest trip from Pittsburgh to St. Louis was searched and found on 17 Nov 2025 with a price of R 1 001

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St. Louis as early as possible.

You can expect to pay from R 1 001 to R 2 827 for a bus ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 001, which is on 2025-11-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Pittsburgh to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

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