Bus Tickets from New York City to Florence, SC, US

Find affordable bus tickets from New York City to Florence, SC, US with flexible options. Book your trip now

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TodayAug 9
from US$131
TomorrowAug 10
from US$131
MonAug 11
from US$107
TueAug 12
from US$111
WedAug 13
from US$112
ThuAug 14
from US$99
FriAug 15
from US$108
SatAug 16

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 10 at
    Departure city: New York City
    Departure location: 95 Canal St
    Arrival time: August 11 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: New York City
    Departure location: 103 Canal St
    Arrival time: August 11 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: New York City
    Departure location: New York Port Authority
    Arrival time: August 11 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: New York City
    Departure location: NYC Midtown (31st St & 8th Ave)
    Arrival time: August 11 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: New York City
    Departure location: 103 Canal St
    Arrival time: August 11 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 4:01 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from New York City to Florence

Average PriceUS$80 - US$296Average Duration14h 45m
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$108 - US$349Average Duration12h 40m
81kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from New York City to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 12 hours 40 minutes, and with fares starting at just US$108, it presents an excellent value for a comfortable ride.

1train per day
12h 40mAverage Duration
US$108Cheapest ticket
81kgCO₂ emissions

Bus New York City to Florence, SC, US: Trip Overview

Average Ticket PriceUS$131
Average Bus Trip Duration14h 45m
Number of daily buses19
Earliest bus departure10:15am
Distance888 km
Latest bus departure11:00pm

New York City to Florence Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from New York City to Florence.

We make sure you can find a bus service from New York City to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from New York City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip New York City - Florence, SC, US

  1. What is the travel distance from New York City to Florence?

    It's about 879 km (545 miles) from New York City to Florence.

  2. What are the departure and arrival locations for buses traveling from New York City to Florence?

    Buses traveling this route start their trip at GW Bridge, in New York City, and end it at Florence Bus Station, in Florence.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-07
US$120
08-08
US$120
Today
US$120
08-10
US$120
08-11
US$120
08-12
US$120
08-13
US$120
08-14
US$120
busbud logoThe cheapest trip from New York City to Florence, SC, US was searched and found on Aug 7, 2025 with a price of US$120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to Florence, SC, US, as early as possible.

You can expect to pay from US$120 to US$307 for a bus ticket from New York City to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$120 which is on 2025-08-10.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from New York City to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New York City to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from New York City to Florence.

Tune out to the fine sounds of your best music playlist on your bus trip from New York City to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from New York City to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to New York City by bus?

Bus from New York City to Florence, SC, US

You can also go to Florence, SC, US by train

Train from New York City to Florence, SC, US

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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