Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Durham Greyhound Bus Station | Florence, SC | No tags | ||||
 | Bus | BP Gas Station | 2301 W Lucas St. | No tags | ||||
| Bus | BP Gas Station | 2301 W Lucas St. | No tags | ||||
| Bus | Durham Greyhound Bus Station | Florence, SC | No tags | ||||
| Bus | BP Gas Station | 2301 W Lucas St. | No tags |
Compare 2 ways to go from Durham to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 7 hours, and with fares starting at just $93, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Florence?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Durham, NC, US to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Durham to Florence?
The cheapest bus tickets from Durham to Florence start from $93. The average price for this route is around $95. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Florence?
The average bus travel time from Durham to Florence is 7h, covering a distance of 215 km. The quickest bus can get you there in 3h 40m and is operated by Wanda Coach.
Which bus companies service the Durham to Florence route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, Wanda Coach.
What are the earliest and latest departure times for the bus from Durham to Florence?
The earliest bus departs from Durham to Florence at 4:20am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Durham to Florence?
A bus trip from Durham to Florence generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Durham to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12050 reviews.
Which bus company has the best Wi-Fi from Durham to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Durham to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Durham to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Florence, SC, US was searched and found on Jan 22, 2026 with a price of $73To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Florence, SC, US, as early as possible.
You can expect to pay from $73 to $86 for a bus ticket from Durham, NC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $73 which is on 2026-01-22.
Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Durham, NC, US to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
