Find coaches from Durham, NC, US to Florence, SC, US

Find affordable coach tickets from Durham, NC, US to Florence, SC, US with flexible options. Book your journey now

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Today11 Aug
from US$67
Tomorrow12 Aug
from US$54
Wed13 Aug
Thu14 Aug
Fri15 Aug
Sat16 Aug
Sun17 Aug
Mon18 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 12 August at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: 13 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 12 August at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: 12 August at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: 12 August at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:

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Compare 2 ways to travel from Durham to Florence

Bus
Average priceUS$38 - US$91Average duration3h 40m
5kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$45 - US$76Average duration8h 25m
20kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 3 hours 40 minutes and with fares starting at just US$38, it presents an excellent value for a comfortable ride.

2bus per day
3h 40mAverage duration
US$38Cheapest ticket
5kgCO₂ emissions

Bus Durham, NC, US to Florence, SC, US: Trip Overview

Average ticket priceUS$67
Average bus trip duration3h 40m
Number of daily buses2
Earliest bus departure04:20
Distance134 miles
Latest bus departure21:15

Durham to Florence Bus

Busbud helps you find a bus from Durham to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Durham to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Durham, NC, US - Florence, SC, US

  1. How far is Florence from Durham by coach?

    The distance between Durham and Florence by coach is approximately 131 miles (210 km).

  2. Is there a way to reach Florence from Durham without a car?

    The best way to go from Durham to Florence without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. Depending on your preferences, carpooling can also be considered as an option.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/08
No data
10/08
US$54
Today
US$60
12/08
US$46
13/08
US$54
14/08
US$60
15/08
US$60
16/08
US$56
busbud logoThe cheapest trip from Durham, NC, US to Florence, SC, US was searched and found on 12 Aug 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Florence, SC, US as early as possible.

You can expect to pay from US$46 to US$67 for a bus ticket from Durham, NC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$46, which is on 2025-08-12.

Usually iLIKEBUS, FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Florence!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Florence.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Florence.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Durham, NC, US to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Durham, NC, US to Florence, SC, US

You can also go to Florence, SC, US by train

Train from Durham, NC, US to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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