Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Opelika (4th Street Station) | Cheapest | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | Fastest |
Last refresh of the prices: Last Monday at 10:43 AM CST.
Get from Mobile to Opelika
The journey takes about 4 hours 25 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Opelika?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Based on 87412 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $64
Frequently asked questions about travelling from Mobile to Opelika by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Opelika?
The cheapest bus tickets from Mobile to Opelika start from $64. The average price for this route is around $88. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Opelika?
The average bus travel time from Mobile to Opelika is 4h 25m, covering a distance of 340 km. The quickest bus can get you there in 4h 25m and is operated by Greyhound.
Which bus companies service the Mobile to Opelika route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Mobile to Opelika?
The earliest bus departs from Mobile to Opelika at 8:30am. And the latest bus departs at 11:40am.
What are the CO₂ emissions for the bus trip from Mobile to Opelika?
A bus trip from Mobile to Opelika generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Opelika was searched and found on Dec 4, 2025 with a price of $55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Opelika, as early as possible.
You can expect to pay from $55 to $82 for a bus ticket from Mobile to Opelika based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-12-04.
