Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags |
Get from Mobile to Opelika
The journey takes about 4 hours 25 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Where are the popular stops in Mobile and Opelika?
Frequently asked questions about traveling from Mobile to Opelika by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Opelika was searched and found on Nov 13, 2025 with a price of $49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Opelika, as early as possible.
Top traveled bus routes
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Popular Buses Connecting Mobile
Buses Leaving from Mobile
- Bus from Mobile to Montreal
- Bus Mobile - Memphis
- Mobile - Lebanon
- Bus from Mobile to Temple
- Bus Mobile - Holland
- Mobile - Atlanta
- Bus from Mobile to New Orleans
- Bus Mobile - Birmingham
- Mobile - Huntsville
- Bus from Mobile to Biloxi
- Bus Mobile - Jacksonville
- Mobile - Miami
- Bus from Mobile to Houston
- Bus Mobile - Orlando
- Mobile - Montgomery
Buses Going to Mobile
- Bus from Orange to Mobile
- Bus Huntington - Mobile
- Holland - Mobile
- Bus from Reno to Mobile
- Bus Memphis - Mobile
- Houston - Mobile
- Bus from New York City to Mobile
- Bus Birmingham - Mobile
- Atlanta - Mobile
- Bus from New Orleans to Mobile
- Bus Orlando - Mobile
- Huntsville - Mobile
- Bus from Montgomery to Mobile
- Bus Tampa - Mobile
- Miami - Mobile
Popular Buses Connecting Opelika
Buses Leaving from Opelika
- Bus from Opelika to Mobile
- Bus Opelika - Macon
- Opelika - Atlanta
- Bus from Opelika to Birmingham
- Bus Opelika - Brunswick
- Opelika - Norfolk
- Bus from Opelika to Auburn
- Bus Opelika - Columbus
- Opelika - Montgomery
- Bus from Opelika to Cincinnati
- Bus Opelika - Miami
- Opelika - Dallas
- Bus from Opelika to New York City
- Bus Opelika - Wichita
- Opelika - Dothan
Buses Going to Opelika
- Bus from Auburn to Opelika
- Bus Chattanooga - Opelika
- Tampa - Opelika
- Bus from Atlanta to Opelika
- Bus Los Angeles - Opelika
- New York City - Opelika
- Bus from Indianapolis to Opelika
- Bus Orlando - Opelika
- Houston - Opelika
- Bus from Mobile to Opelika
- Bus Montgomery - Opelika
- Jacksonville - Opelika
- Bus from Gainesville to Opelika
- Bus Birmingham - Opelika
- Tulsa - Opelika
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Miami - Tampa
- Austin - Houston
- Bus from Houston to San Antonio
- Bus Seattle - Leavenworth
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Providence - New York City