Bus Tickets from Mexicali to Guadalajara, MX

Next departures

Next departures for Mexicali to Guadalajara on September 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ACN
Mexicali Centro Civico - Stop
Nueva CentralCheapest
Tufesa
Tufesa
Zapopan GuadalajaraFastest
Elite Select
Terminal de Autobuses de Mexicali
Nueva Central Camionera, Estación Central de Autobuses de GuadalajaraNo tags
ACN
Mexicali(Ejido Puebla) - Stop
Nueva CentralNo tags
Tufesa
Tufesa
Nueva CentralNo tags

Last refresh of the prices: Yesterday at 7:51 PM PDT.

Accepted payments

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Compare 2 ways to go from Mexicali to Guadalajara

Bus
Average PriceUS$94 - US$248Average Duration1d 7h
45kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$89 - US$89Average Duration1d 1h
76kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Mexicali to Guadalajara

Among the sustainable travel choices, the bus stands out as a good way to reach Guadalajara. The journey takes about 1 day, 7 hours, and with fares starting at just US$94, it presents an excellent value for a comfortable ride.

20bus per day
1d 7hAverage Duration
US$94Cheapest ticket
45kgCO₂ emissions

Bus Mexicali to Guadalajara, MX: Trip Overview

Average Ticket PriceUS$177
Average Bus Trip Duration1d 7h
Number of daily buses20
Earliest bus departure12:50am
Distance1782 km
Latest bus departure11:59pm

Mexicali to Guadalajara Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mexicali to Guadalajara.

We make sure you can find a bus service from Mexicali to Guadalajara from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Mexicali to Guadalajara, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mexicali - Guadalajara, MX

  1. What is the distance between Mexicali and Guadalajara?

    The distance covered from Mexicali to Guadalajara is 1790 km (1110 miles).

  2. What are the departure and arrival locations for buses traveling from Mexicali to Guadalajara?

    Buses traveling this route start their trip at Terminal de Autobuses de Mexicali, in Mexicali, and end it at Nueva Central, in Guadalajara.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-23
US$165
09-24
US$87
Today
US$87
09-26
US$87
09-27
US$87
09-28
US$87
09-29
US$87
09-30
US$87
busbud logoThe cheapest trip from Mexicali to Guadalajara, MX was searched and found on Sep 30, 2025 with a price of US$87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guadalajara, MX, as early as possible.

You can expect to pay from US$87 to US$165 for a bus ticket from Mexicali to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$87 which is on 2025-09-30.

Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mexicali to Guadalajara but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexicali to Guadalajara, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mexicali to Guadalajara that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexicali to Guadalajara.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Mexicali by bus?

Bus from Guadalajara, MX to Mexicali

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