Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Sur | Perrache | Cheapest | ||||
 | Bus | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Lyon Perrache Bus Station | Fastest | ||||
 | Bus | Estación Sur | Lyon - Gerland Bus Station | No tags | ||||
| Bus | Estación Sur | Perrache | No tags | ||||
 | Bus | Madrid (South) | Lyon (Gerland) | No tags |
Last refresh of the prices: Today at 3:19 PM CET.
Compare 2 ways to go from Madrid to Lyon
Among the sustainable travel choices, the Carpool stands out as a good way to reach Lyon. The journey takes about 12 hours 40 minutes, and with fares starting at just $126, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$50 - $267 | Average Duration18h 25m | 23kg CO₂e | ||
Carpool | Average Price$126 - $203 | Average Duration12h 40m | 38kg CO₂e |
Where are the popular stops in Madrid and Lyon?
Stops in Madrid
- BMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Madrid to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Madrid to Lyon?
The cheapest bus tickets from Madrid to Lyon start from $50. The average price for this route is around $118. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Madrid to Lyon?
The average bus travel time from Madrid to Lyon is 18h 25m, covering a distance of 912 km. The quickest bus can get you there in 15h 25m and is operated by BlaBlaCar Bus.
Which bus companies service the Madrid to Lyon route?
Several major bus companies operate on this route with 15 buses available per day, including services from FlixBus, BlaBlaCar Bus, ALSA, Union Ivkoni, KLR Bus.
What are the earliest and latest departure times for the bus from Madrid to Lyon?
The earliest bus departs from Madrid to Lyon at 12:14am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Madrid to Lyon?
A bus trip from Madrid to Lyon generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Madrid to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61223 reviews.
Which bus company has the best Wi-Fi from Madrid to Lyon?
Based on Busbud reviews, the bus company KLR Bus has the highest Wi-Fi rating with a score of 4.5.
Which bus company has the best on-time performance from Madrid to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Madrid to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is KLR Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madrid to Lyon was searched and found on Feb 13, 2026 with a price of $56To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Lyon, as early as possible.
You can expect to pay from $56 to $266 for a bus ticket from Madrid to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2026-02-13.
What's the cheapest way to go from Madrid to Lyon?
The Bus is the cheapest travel choice for this destination
