Next departures from Madrid to Lyon on 10 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
Cheapest
Bus
Madrid (South)
Perrache
Fastest
Bus
Estación Sur
Lyon - Perrache Bus Station
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Perrache
No tags
Next departures from Madrid to Lyon on 11 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
Cheapest
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
Fastest
Bus
Estación Sur
Lyon - Perrache Bus Station
No tags
Bus
Estación Sur
Lyon - Perrache Bus Station
No tags
Bus
Aeropuerto Madrid - Barajas T4 (E)
Lyon - Perrache Bus Station
No tags
Next departures from Madrid to Lyon on 12 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
Cheapest
Bus
Madrid (South)
Perrache
Fastest
Bus
Estación Sur
Lyon - Perrache Bus Station
No tags
Bus
Estación Sur
Perrache
No tags
Bus
Avenida de América Metro
Lyon - Perrache Bus Station
No tags
Next departures from Madrid to Lyon on 13 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Estación Sur
Lyon - Perrache Bus Station
Cheapest
Bus
Madrid (South)
Perrache
Fastest
Bus
Estación Sur
Lyon - Perrache Bus Station
No tags
Bus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Lyon Perrache Bus Station
No tags
Bus
Madrid (South)
Perrache
No tags
Last refresh of the prices: Today at 05:06 CET.
Compare 2 ways to travel from Madrid to Lyon
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 17 hours 40 minutes and with fares starting at just £110, it presents an excellent value for a comfortable ride.
Based on 11531 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £44
Based on 11197 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. BlaBlaCar Bus ticket prices on this trip start at £38
Based on 60874 reviews, the company was rated 4.3 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. ALSA ticket prices on this trip start at £69
Based on 1950 reviews, the company was rated 2.6 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi-Fi. Union Ivkoni ticket prices on this trip start at £28
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at £58
Frequently asked questions about travelling by bus from Madrid to Lyon
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Madrid to Lyon?
The cheapest coach tickets from Madrid to Lyon start from £28. The average price for this route is around £83. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Madrid to Lyon?
The average bus journey time from Madrid to Lyon is 19h 14m, covering a distance of 565 miles. The fastest bus can take you there in 16h 25m and is operated by BlaBlaCar Bus.
Which bus companies service the Madrid to Lyon route?
What is the earliest and latest departure time for the bus from Madrid to Lyon?
The earliest bus departs from Madrid to Lyon at 00:14. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Madrid to Lyon?
A bus journey from Madrid to Lyon produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Madrid to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 60868 reviews.
Which company has the best Wi-Fi from Madrid to Lyon?
Based on Busbud reviews, the bus company KLR Bus has the best Wi-Fi rating with a score of 4.5.
Which bus company offers the most punctual service from Madrid to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Madrid to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is KLR Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
04/12
£92
05/12
£110
Today
£50
07/12
£47
08/12
£43
09/12
£43
10/12
£43
11/12
£43
The cheapest trip from Madrid to Lyon was searched and found on 8 Dec 2025 with a price of £43
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Lyon as early as possible.
You can expect to pay from £43 to £184 for a bus ticket from Madrid to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at £43, which is on 2025-12-08.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Madrid to Lyon?
The bus is the cheapest travel choice for this destination
The cheapest trip from Madrid to Lyon was searched and found on 8 Dec 2025 with a price of £43
The bus is the cheapest travel choice for this destination
