Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | La Crosse MTU Transit Center | Minneapolis | Cheapest | ||||
| Bus | La Crosse MTU Transit Center | Minneapolis (U of MN - Huron Blvd) | Fastest | ||||
Jefferson Lines + Jefferson Lines | Bus | 632 17th Street North | Minneapolis (Mall of America) | No tags | ||||
| Bus | La Crosse MTU Transit Center | MSP Airport T1 (Minneapolis International Airport) | No tags | ||||
Jefferson Lines + Jefferson Lines | Bus | La Crosse MTU Transit Center | MSP Airport T1 (Minneapolis International Airport) | No tags |
Last refresh of the prices: Last Saturday at 1:37 PM CST.
Get from La Crosse to Minneapolis
The journey takes about 6 hours 5 minutes, and with fares starting at just $43, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 759 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at $43
Jefferson Lines La Crosse Minneapolis recent customer reviews
Comfy trip. On time. Friendly and competent driver.
Melora P.
Frequently asked questions about travelling from La Crosse, WI to Minneapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from La Crosse to Minneapolis?
The cheapest bus tickets from La Crosse to Minneapolis start from $43. The average price for this route is around $48. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from La Crosse to Minneapolis?
The average bus travel time from La Crosse to Minneapolis is 6h 5m, covering a distance of 203 km. The quickest bus can get you there in 4h 5m and is operated by Jefferson Lines.
Which bus companies service the La Crosse to Minneapolis route?
Several major bus companies operate on this route with 13 buses available per day.
What are the earliest and latest departure times for the bus from La Crosse to Minneapolis?
The earliest bus departs from La Crosse to Minneapolis at 12:25pm. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from La Crosse to Minneapolis?
A bus trip from La Crosse to Minneapolis generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Crosse, WI to Minneapolis was searched and found on Dec 4, 2025 with a price of $42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Minneapolis, as early as possible.
You can expect to pay from $42 to $119 for a bus ticket from La Crosse, WI to Minneapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2025-12-04.
