Bus Tickets from Greenville (SC) to Winston-Salem

Find affordable bus tickets from Greenville (SC) to Winston-Salem with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 19
from US$35
TomorrowJun 20
from US$36
SatJun 21
SunJun 22
from US$37
MonJun 23
TueJun 24
WedJun 25
from US$33
ThuJun 26

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 20 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 20 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 20 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: June 20 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: June 20 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 20 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 20 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: June 20 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: June 20 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: June 20 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 10:08 AM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Greenville to Winston-Salem

Bus
Average PriceUS$32 - US$158Average Duration3h 10m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$59 - US$59Average Duration7h 42m
22kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the train from Greenville to Winston-Salem

Among the sustainable travel choices, the train stands out as a good way to reach Winston-Salem. The journey takes about 7 hours 42 minutes, and with fares starting at just US$59, it presents an excellent value for a comfortable ride.

2train per day
7h 42mAverage Duration
US$59Cheapest ticket
22kgCO₂ emissions

Bus Greenville to Winston-Salem: Trip Overview

Average Ticket PriceUS$137
Average Bus Trip Duration3h 10m
Number of daily buses3.642857142857143
Earliest bus departure10:50am
Distance241 km
Latest bus departure12:34pm

Greenville to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - Winston-Salem

  1. What is the distance between Greenville and Winston-Salem?

    The distance between Greenville and Winston-Salem is around 240 km (149 miles).

  2. What are the departure and arrival locations for buses traveling from Greenville to Winston-Salem?

    Buses traveling this route start their trip at Guadalajara Supermarket Bus Stop, in Greenville, and end it at Winston Salem Greyhound Bus Station, in Winston-Salem.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-17
No data
06-18
US$31
Today
US$28
06-20
US$29
06-21
No data
06-22
US$30
06-23
US$35
06-24
US$26
busbud logoThe cheapest trip from Greenville to Winston-Salem was searched and found on Jun 24, 2025 with a price of US$26

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Winston-Salem, as early as possible.

You can expect to pay from US$26 to US$130 for a bus ticket from Greenville to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$26 which is on 2025-06-24.

Usually Expreso will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Winston-Salem will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville by bus?

Bus from Greenville to Winston-Salem

You can also go to Winston-Salem by train

Train from Greenville to Winston-Salem

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville

Popular Buses Connecting Winston-Salem

Buses Leaving from Winston-Salem

Buses Going to Winston-Salem