Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Lake Charles (City Point) | CheapestFastest |
Last refresh of the prices: Yesterday at 4:45 AM EST.
Compare 2 ways to go from Greenville to Lake Charles
Among the sustainable travel choices, the bus stands out as a good way to reach Lake Charles. The journey takes about 1 day, 1 hour, and with fares starting at just $252, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Lake Charles?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Lake Charles
- A
Lake Charles Greyhound
1825 I-10, Lake Charles, LA 70601, USA - B
Waffle House Lake Charles
804 N Lakeshore Dr, Lake Charles, LA 70601, USA
Compare bus companies
Based on 87402 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $252
Frequently asked questions about travelling from Greenville, SC to Lake Charles by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Lake Charles?
The cheapest bus tickets from Greenville to Lake Charles start from $252. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Lake Charles?
The average bus travel time from Greenville to Lake Charles is 1d 1h, covering a distance of 1142 km. The quickest bus can get you there in 18h 40m and is operated by Greyhound.
Which bus companies service the Greenville to Lake Charles route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Greenville to Lake Charles?
The earliest bus departs from Greenville to Lake Charles at 2:45pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Lake Charles?
A bus trip from Greenville to Lake Charles generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Lake Charles was searched and found on Nov 27, 2025 with a price of $280To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Lake Charles, as early as possible.
What's the cheapest way to go from Greenville, SC to Lake Charles?
The bus is the cheapest travel choice for this destination
