Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Lake Charles (City Point) | CheapestFastest |
Last refresh of the prices: Yesterday at 4:45 AM EST.
Compare 2 ways to go from Greenville to Lake Charles
Among the sustainable travel choices, the bus stands out as the good way to reach Lake Charles. The journey takes about 1 day, 1 hour and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Lake Charles?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Lake Charles
- A
Lake Charles Greyhound
1825 I-10, Lake Charles, LA 70601, USA - B
Waffle House Lake Charles
804 N Lakeshore Dr, Lake Charles, LA 70601, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Greenville, SC to Lake Charles by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Lake Charles?
The cheapest bus tickets from Greenville to Lake Charles start from $175. The average price for this route is around $175. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Lake Charles?
The average bus trip duration from Greenville to Lake Charles is 1d 1h, covering a distance of 708 miles (1142 km). The quickest bus can get you there in 18h 40m and is operated by Greyhound.
Which bus companies service the Greenville to Lake Charles route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Greenville to Lake Charles?
The earliest bus departs from Greenville to Lake Charles at 2:45pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Lake Charles?
A bus trip from Greenville to Lake Charles generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Lake Charles was searched and found on Nov 27, 2025 with a price of $194To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Lake Charles, as early as possible.
What's the cheapest way to go from Greenville, SC to Lake Charles?
The bus is the cheapest travel choice for this destination
