Bus from Frankfurt am Main to Prague: Tickets & Schedules

Next bus departures

Next departures for Frankfurt am Main to Prague on December 7
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
KLR BusBus
    		Frankfurt Main Airport P36
    		FlorencCheapest
    RegioJetBus
    		Frankfurt - Main bus station
    		FlorencFastest
    FlixbusBus
    		Frankfurt Hbf
    		PRG AirportNo tags
    KLR BusBus
      		Frankfurt Main Train Station
      		FlorencNo tags
      FlixbusBus
      		Frankfurt Hbf
      		PRG AirportNo tags

      Last refresh of the prices: Today at 8:06 AM CET.

      Compare 3 ways to go from Frankfurt am Main to Prague

      We recommend carpooling

      Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 20 minutes, and with fares starting at just $40, it presents an excellent value for a comfortable ride.

      2carpool per day
      5h 20mAverage Duration
      410 kmDistance
      17kgCO₂ emissions
      Bus
      		Average Price$23 - $197Average Duration8h 56m
      10kg CO₂e
      Train
      		Average Price$45 - $359Average Duration7h 47m
      10kg CO₂e
      Carpool
      		Average Price$40 - $81Average Duration5h 20m
      17kg CO₂e

      Frequently asked questions about travelling from Frankfurt am Main to Prague by bus

      Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

      1. How much is the bus ticket from Frankfurt am Main to Prague?

        The cheapest bus tickets from Frankfurt am Main to Prague start from $23. The average price for this route is around $64. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

      2. How long is the bus ride from Frankfurt am Main to Prague?

        The average bus travel time from Frankfurt am Main to Prague is 8h 56m, covering a distance of 412 km. The quickest bus can get you there in 6h 15m and is operated by BlaBlaCar Bus.

      3. Which bus companies service the Frankfurt am Main to Prague route?

        Several major bus companies operate on this route with 31 buses available per day, including services from FlixBus, KLR Bus, Racic Eurobus, RegioJet, BlaBlaCar Bus, Musil Tour, Infobus, LEX CLUB.

      4. What are the earliest and latest departure times for the bus from Frankfurt am Main to Prague?

        The earliest bus departs from Frankfurt am Main to Prague at 12:05am. And the latest bus departs at 11:59pm.

      5. What are the CO₂ emissions for the bus trip from Frankfurt am Main to Prague?

        A bus trip from Frankfurt am Main to Prague generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

      6. What is the best bus company from Frankfurt am Main to Prague?

        According to Busbud customers, the highest-rated bus company on this route is KLR Bus, with an average rating of 4.2 out of 5 stars based on 19 reviews.

      7. Which bus company has the best Wi-Fi from Frankfurt am Main to Prague?

        Based on Busbud reviews, the bus company KLR Bus has the highest Wi-Fi rating with a score of 4.5.

      8. Which bus company has the best on-time performance from Frankfurt am Main to Prague?

        According to Busbud traveller reviews, the most punctual bus company on this route is Infobus, with a punctuality rating of 4.3 out of 5 stars.

      9. Which bus company has the cleanest buses from Frankfurt am Main to Prague?

        According to Busbud traveller reviews, the bus company with the cleanest buses on this route is KLR Bus, with a cleanliness rating of 5.0 out of 5 stars.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      12-04
      $55
      12-05
      $75
      Today
      $48
      12-07
      $27
      12-08
      $27
      12-09
      $44
      12-10
      $28
      12-11
      $60
      busbud logoThe cheapest trip from Frankfurt am Main to Prague was searched and found on Dec 7, 2025 with a price of $27

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.

      You can expect to pay from $27 to $173 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $27 which is on 2025-12-07.

      Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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