Next departures from Frankfurt am Main to Prague on 14 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
FRA Frankfurt airport
Prague (Na Knížecí)
No tags
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
No tags
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
No tags
Bus
Frankfurt Hbf
Prague (Main Railway Station)
No tags
Next departures from Frankfurt am Main to Prague on 15 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Florenc
CheapestFastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Next departures from Frankfurt am Main to Prague on 16 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt central
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures from Frankfurt am Main to Prague on 17 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Next departures from Frankfurt am Main to Prague on 18 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Next departures from Frankfurt am Main to Prague on 19 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Next departures from Frankfurt am Main to Prague on 20 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Next departures from Frankfurt am Main to Prague on 21 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Last refresh of the prices: Today at 2:38 PM CET.
Compare 3 ways to travel from Frankfurt am Main to Prague
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 20 minutes and with fares starting at just R 444, it presents an excellent value for a comfortable ride.
Based on 11307 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 514
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at R 325
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the value for money but often complained with the Wi-Fi. RegioJet ticket prices on this trip start at R 584
Based on 11115 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. BlaBlaCar Bus ticket prices on this trip start at R 520
Musil Tour offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is R 995, you can find tickets starting at R 994. The trip between the two cities usually takes about 580.
Based on 490 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. Infobus ticket prices on this trip start at R 905
LEX CLUB offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is R 561, you can find tickets starting at R 556. The trip between the two cities usually takes about 870.
Frequently asked questions about travelling from Frankfurt am Main to Prague by bus
How much does a bus ticket from Frankfurt am Main to Prague cost?
The bus ticket price from Frankfurt am Main to Prague starts at R 325. The best way to find cheap bus tickets from Frankfurt am Main to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Frankfurt am Main to Prague?
The average travel time between Frankfurt am Main and Prague is around 8h 56m, although the fastest bus will take about 6h 18m. This is the time it takes to travel the 410 km that separates the two cities.
How many daily bus connections are there between Frankfurt am Main and Prague?
The number of buses from Frankfurt am Main to Prague can differ depending on the day of the week. On average, there are 26 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Frankfurt am Main to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Frankfurt am Main to Prague?
When taking the bus from Frankfurt am Main to Prague, you can travel comfortably and safely with FlixBus, KLR Bus, RegioJet.
What are the departure and arrival stations when taking the bus from Frankfurt am Main to Prague?
Buses travelling between Frankfurt am Main and Prague leave from Frankfurt Airport or Hbf and arrive at Florenc, Černý Most, Zličín.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/11
R 625
13/11
R 1 090
Today
R 392
15/11
R 626
16/11
R 300
17/11
R 277
18/11
R 254
19/11
R 277
The cheapest trip from Frankfurt am Main to Prague was searched and found on 18 Nov 2025 with a price of R 254
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague as early as possible.
You can expect to pay from R 254 to R 1 695 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at R 254, which is on 2025-11-18.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Frankfurt am Main to Prague?
The bus is the cheapest travel choice for this destination
The cheapest trip from Frankfurt am Main to Prague was searched and found on 18 Nov 2025 with a price of R 254
The bus is the cheapest travel choice for this destination