Bus Tickets from Detroit (MI) to Panama City, US

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TodayJun 3
TomorrowJun 4
from US$228
ThuJun 5
FriJun 6
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TueJun 10

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 4 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 5 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 4 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: June 6 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 1:54 PM EDT.

Prices and availability are subject to change.

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Bus Detroit to Panama City: Trip Overview

Average Ticket PriceUS$220
Average Bus Trip Duration1d 6h
Number of daily buses2
Earliest bus departure6:40am
Distance1371 km
Latest bus departure11:25pm

Detroit to Panama City Bus

Busbud helps you find a bus from Detroit to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Detroit to Panama City from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Detroit to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Detroit (MI) - Panama City, US

  1. How long is the bus ride from Detroit to Panama City?

    The trip from Detroit to Panama City will take on average 1d 6h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1d 6h.

  2. How far is Detroit from Panama City?

    Detroit and Panama City are 1375 km (853 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Detroit to Panama City?

    Buses departing from Detroit Bus Station in Detroit will take you to Panama City Greyhound Bus Station in Panama City.

  4. What is the cheapest way to get from Detroit to Panama City?

    If you're on a budget, consider traveling by bus to Panama City from Detroit; it tends to be more affordable. With a starting ticket price of US$213, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Detroit to Panama City?

    The bus from Detroit to Panama City will cost you US$220, on average.

  6. Can I take an overnight bus from Detroit to Panama City?

    Yes! If you're heading from Detroit to Panama City, you'll find buses departing until 11:25pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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Today
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06-04
US$220
06-05
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busbud logoThe cheapest trip from Detroit to Panama City was searched and found on Jun 4, 2025 with a price of US$220

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Panama City, as early as possible.

You can expect to pay from US$220 to US$241 for a bus ticket from Detroit to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at US$220 which is on 2025-06-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Panama City, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Panama City that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Detroit to Panama City.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Detroit by bus?

Bus from Detroit to Panama City

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