Bus Des Moines to Sioux City: Trip Overview
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Based on 753 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the staff and the temperature but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at US$173
Des Moines to Sioux City Bus
With Busbud, comparing and booking tickets for a bus from Des Moines to Sioux City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to Sioux City.
Whether it is cheap bus tickets or more luxurious buses going to Sioux City from Des Moines, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Des Moines and Sioux City?
Frequently asked questions on the trip Des Moines - Sioux City
How far is Des Moines from Sioux City?
The distance between Des Moines and Sioux City is approximately 252 km (156 miles).
What are the departure and arrival locations for buses traveling from Des Moines to Sioux City?
Buses departing from Jefferson/Trailways Depot in Des Moines will take you to W Maple St in Sioux City.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Sioux City was searched and found on Aug 8, 2025 with a price of US$168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Sioux City, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Des Moines to Sioux City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to Sioux City.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Sioux City.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Sioux City.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
- Bus from Des Moines to Iowa City
- Bus Des Moines - Washington
- Des Moines - Omaha
- Bus from Des Moines to Denver
- Bus Des Moines - Cedar Rapids
- Des Moines - Chicago
- Bus from Des Moines to Jackson
- Bus Des Moines - Ames
- Des Moines - Keokuk
- Bus from Des Moines to Las Vegas
- Bus Des Moines - San Diego
- Des Moines - Baltimore
- Bus from Des Moines to New York City
- Bus Des Moines - Lubbock
- Des Moines - Clear Lake
Buses Going to Des Moines
- Bus from Washington to Des Moines
- Bus Chicago - Des Moines
- Minneapolis - Des Moines
- Bus from Las Vegas to Des Moines
- Bus Staples - Des Moines
- Iowa City - Des Moines
- Bus from Vermillion to Des Moines
- Bus Waterloo - Des Moines
- Ithaca - Des Moines
- Bus from Newark to Des Moines
- Bus Bloomington - Des Moines
- San Jose - Des Moines
- Bus from Latimer to Des Moines
- Bus Lincoln - Des Moines
- Eau Claire - Des Moines
Popular Buses Connecting Sioux City
Buses Leaving from Sioux City
- Bus from Sioux City to Chicago
- Bus Sioux City - Sioux Falls
- Sioux City - Glendive
- Bus from Sioux City to Tulsa
- Bus Sioux City - Austin
- Sioux City - Miami
- Bus from Sioux City to El Paso
- Bus Sioux City - Minneapolis
- Sioux City - Clear Lake
- Bus from Sioux City to Oklahoma City
- Bus Sioux City - Omaha
- Sioux City - Maple Grove
- Bus from Sioux City to Minot
- Bus Sioux City - Des Moines
- Sioux City - Saint Paul
Buses Going to Sioux City
- Bus from Monterrey to Sioux City
- Bus Bismarck - Sioux City
- Vermillion - Sioux City
- Bus from Vivian to Sioux City
- Bus Billings - Sioux City
- Dallas - Sioux City
- Bus from Austin to Sioux City
- Bus El Paso - Sioux City
- Houston - Sioux City
- Bus from Minneapolis to Sioux City
- Bus Omaha - Sioux City
- Kansas City - Sioux City
- Bus from Burnsville to Sioux City
- Bus Oklahoma City - Sioux City
- Faribault - Sioux City
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Los Angeles to San Francisco
- Bus Baton Rouge - New Orleans