Trains leaving Monday
One passenger / one way
- This trip is recommended because it is: CheapestDeparture time: August 11 atDeparture city: FlorenceDeparture location: Florence StationArrival time: August 12 atDestination city: HarrisburgDestination location: Harrisburg, PAOperated by: Amtrak
Vehicle: TrainDuration: - This trip is recommended because it is: FastestDeparture time: August 11 atDeparture city: FlorenceDeparture location: Florence StationArrival time: August 12 atDestination city: HarrisburgDestination location: Harrisburg, PAOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 11 atDeparture city: FlorenceDeparture location: Florence StationArrival time: August 12 atDestination city: HarrisburgDestination location: Harrisburg, PAOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 11 atDeparture city: FlorenceDeparture location: Florence StationArrival time: August 12 atDestination city: HarrisburgDestination location: Harrisburg, PAOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 11 atDeparture city: FlorenceDeparture location: Florence StationArrival time: August 12 atDestination city: HarrisburgDestination location: Harrisburg, PAOperated by: AmtrakVehicle: TrainDuration:
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Compare 2 ways to go from Florence to Harrisburg.
Busbud recommends taking the train from Florence to HarrisburgAmong the sustainable travel choices, the train stands out as the good way to reach Harrisburg. The journey takes about 14 hours 54 minutes and with fares starting at just $178, it presents an excellent value for a comfortable ride.
Train Florence, SC, US to Harrisburg: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5379 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $178
Florence to Harrisburg Train
Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Florence to Harrisburg.
We make sure you can find a train service from Florence to Harrisburg from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Harrisburg from Florence, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Florence, SC, US - Harrisburg
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Harrisburg was searched and found on Aug 11, 2025 with a price of $197To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Harrisburg, as early as possible.
You can expect to pay from $197 to $543 for a train ticket from Florence, SC, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $197 which is on 2025-08-11.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Florence and Harrisburg is also a great way to travel to arrive in the city centre and save more time for your stay in Harrisburg.
Regional train? High-speed train? Whichever train to Harrisburg you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Florence and Harrisburg, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Florence to Harrisburg while indulging in miles on end of beautiful scenic views.
Did you know?
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Top Traveled Train Routes
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