Next departures for Chicago to Jefferson City on November 14
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Next departures for Chicago to Jefferson City on November 15
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Chicago (Union Station), IL
Jefferson City, MO
CheapestFastest
Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Next departures for Chicago to Jefferson City on November 16
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Chicago (Union Station), IL
Jefferson City, MO
CheapestFastest
Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Next departures for Chicago to Jefferson City on November 17
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Chicago (Union Station), IL
Jefferson City, MO
CheapestFastest
Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Next departures for Chicago to Jefferson City on November 18
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Chicago (Union Station), IL
Jefferson City, MO
CheapestFastest
Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Next departures for Chicago to Jefferson City on November 19
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Recommended
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Chicago (Union Station), IL
Jefferson City, MO
CheapestFastest
Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Chicago (Union Station), IL
Jefferson City, MO
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Last refresh of the prices: Yesterday at 12:20 PM CST.
Compare 2 ways to go from Chicago to Jefferson City
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Based on 5584 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $49
Amtrak Chicago Jefferson City recent customer reviews
I didn’t like how chippy the conductors and monitors were
Frequently asked questions about traveling from Chicago to Jefferson City, MO by train
How much does a train ticket from Chicago to Jefferson City cost?
The average train ticket price from Chicago to Jefferson City is $59. The best way to find train tickets from Chicago to Jefferson City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Chicago to Jefferson City?
A train trip between Chicago and Jefferson City is around 7h 46m, although the fastest train will take about 7h 46m. This is the time it takes to travel the 329 miles that separates the two cities.
How many daily trains are there between Chicago and Jefferson City?
The number of trains from Chicago to Jefferson City can differ depending on the day of the week. On average, there are 2. Some trains are direct while others have layovers. Simplify your train trip from Chicago to Jefferson City by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Chicago to Jefferson City?
When taking the train from Chicago to Jefferson City, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/12
$55
11/13
$46
Today
$81
11/15
$46
11/16
$81
11/17
$81
11/18
$55
11/19
$55
The cheapest trip from Chicago to Jefferson City, MO was searched and found on Nov 13, 2025 with a price of $46
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Jefferson City, MO, as early as possible.
You can expect to pay from $46 to $335 for a train ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-11-15.
What's the cheapest way to go from Chicago to Jefferson City, MO?
The train is the cheapest travel choice for this destination
The best way to travel between Chicago and Jefferson City, MO is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $59 on average. If you're on a budget, you'll find cheap tickets from $49. If you're looking for the fastest way to get to Jefferson City, MO, choose the train, as it will take you from Chicago to Jefferson City, MO in about 7h 46m - that's the fastest way to get there!
The cheapest trip from Chicago to Jefferson City, MO was searched and found on Nov 13, 2025 with a price of $46
The train is the cheapest travel choice for this destination
