Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Jefferson City, MO | Chicago (Union Station), IL | CheapestFastest | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags | |||||
| Jefferson City, MO | Chicago (Union Station), IL | No tags |
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Compare 2 ways to go from Jefferson City to Chicago.
Busbud recommends taking the train from Jefferson City to ChicagoAmong the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 8 hours 11 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Train Jefferson City, MO to Chicago: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5438 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $49
Jefferson City to Chicago Train
With Busbud, comparing and booking tickets for a train from Jefferson City to Chicago is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train service from Jefferson City to Chicago.
Whether it is train tickets or first class train tickets going to Chicago from Jefferson City, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Jefferson City, MO - Chicago
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jefferson City, MO to Chicago was searched and found on Sep 2, 2025 with a price of $55To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jefferson City, MO to Chicago, as early as possible.
You can expect to pay from $55 to $353 for a train ticket from Jefferson City, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-09-02.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Jefferson City to Chicago is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Chicago, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Jefferson City and Chicago, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Jefferson City to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
What's the cheapest way to go from Jefferson City, MO to Chicago?
The train is the cheapest travel choice for this destinationThe best way to travel between Jefferson City, MO and Chicago is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $58 on average. If you're on a budget, you'll find cheap tickets from $49. If you're looking for the fastest way to get to Chicago, choose the train, as it will take you from Jefferson City, MO to Chicago in about 8h 11m - that's the fastest way to get there!
Top Traveled Train Routes
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