Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags | ||||
| Train | Durham Station | Greyhound Amtrak Station | No tags |
Compare 2 ways to go from Durham to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 20 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5781 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $153
Frequently asked questions about traveling from Durham, NC, US to Indianapolis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Durham to Indianapolis?
The cheapest train tickets from Durham to Indianapolis start from $153. The average price for this train route is around $175. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Durham to Indianapolis?
The average train ride duration from Durham to Indianapolis is 1d 9h, covering a distance of 473 miles (762 km). The quickest train can get you there in 1d 9h and is operated by Amtrak.
Which train operators service the Durham to Indianapolis route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Durham to Indianapolis?
The earliest train departs from Durham to Indianapolis at 7:06pm. And the latest train departs at 7:58pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on Apr 4, 2026 with a price of $146To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to Indianapolis, as early as possible.
You can expect to pay from $146 to $1,314 for a train ticket from Durham, NC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $146 which is on 2026-04-04.
What's the cheapest way to go from Durham, NC, US to Indianapolis?
The Train is the cheapest travel choice for this destinationThe best way to travel between Durham, NC, US and Indianapolis is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $175 on average. If you're on a budget, you'll find cheap tickets from $153. If you're looking for the fastest way to get to Indianapolis, choose the train, as it will take you from Durham, NC, US to Indianapolis in about 23h 20m - that's the fastest way to get there!
