Bus Tickets from Winston-Salem to Indianapolis

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TodayJun 18
TomorrowJun 19
FriJun 20
SatJun 21
SunJun 22
from $101
MonJun 23
TueJun 24
WedJun 25

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 22 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: June 23 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 22 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: June 23 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: June 23 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: June 23 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 22 at
    Departure city: Winston-Salem
    Departure location: Winston Salem Greyhound Bus Station
    Arrival time: June 23 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Winston-Salem to Indianapolis: Trip Overview

Average ticket price$157
Average bus trip duration22h 20m
Number of daily buses7
Earliest bus departure6:55am
Distance409 miles (659 km)
Latest bus departure6:15pm

Winston-Salem to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Winston-Salem to Indianapolis.

Bus service from Winston-Salem to Indianapolis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Winston-Salem, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Winston-Salem - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/16
No data
06/17
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Today
No data
06/19
No data
06/20
No data
06/21
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06/22
$101
06/23
No data
busbud logoThe cheapest trip from Winston-Salem to Indianapolis was searched and found on Jun 22, 2025 with a price of $101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Indianapolis, as early as possible.

You can expect to pay from $101 to $146 for a bus ticket from Winston-Salem to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $101 which is on 2025-06-22.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Winston-Salem to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Winston-Salem to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Winston-Salem to Indianapolis.

Make a music playlist for your bus ride from Winston-Salem to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Winston-Salem by bus?

Bus from Winston-Salem to Indianapolis

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