Compare 2 ways to go from Syracuse to Winston-Salem.
Busbud recommends taking the bus from Syracuse to Winston-SalemAmong the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 21 hours and with fares starting at just $112, it presents an excellent value for a comfortable ride.
Bus Syracuse, US to Winston-Salem: Trip Overview
Compare bus companies
Syracuse to Winston-Salem Bus
Busbud helps you find a bus from Syracuse to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Syracuse to Winston-Salem from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Syracuse to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Syracuse and Winston-Salem?
Frequently asked questions for your trip Syracuse, US - Winston-Salem
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Winston-Salem was searched and found on Aug 6, 2025 with a price of $165To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Winston-Salem, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Winston-Salem!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Winston-Salem, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Syracuse to Winston-Salem that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Winston-Salem.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Syracuse, US to Winston-Salem?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.