Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Winston Salem Greyhound Bus Station | CheapestFastest | ||||
| Bus | Syracuse (Regional Transportation Center) | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Last Wednesday at 8:40 PM EST.
Get from Syracuse to Winston-Salem
The journey takes about 21 hours 20 minutes, and with fares starting at just R 2 444, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Winston-Salem?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Syracuse, US to Winston-Salem by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Syracuse to Winston-Salem?
The cheapest bus tickets from Syracuse to Winston-Salem start at R 2 444. The average price for this route is around R 3 111. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Syracuse to Winston-Salem?
The average bus journey time from Syracuse to Winston-Salem is 21h 20m, covering a distance of 851 km. The fastest bus gets you there in 18h 45m and is operated by FlixBus.
Which bus companies service the Syracuse to Winston-Salem route?
What is the earliest and latest departure time for the bus from Syracuse to Winston-Salem?
The earliest bus departs from Syracuse to Winston-Salem at 09:25. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Syracuse to Winston-Salem?
A bus trip from Syracuse to Winston-Salem produces an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Syracuse to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.
Which bus company has the best Wi-Fi from Syracuse to Winston-Salem?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Syracuse to Winston-Salem?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Winston-Salem was searched and found on 31 Jan 2026 with a price of R 2 994To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Winston-Salem as early as possible.
You can expect to pay from R 2 994 to R 3 157 for a bus ticket from Syracuse, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 994, which is on 2026-01-31.
