Bus Tickets from St. Louis to Milwaukee

Next departures

Next departures for St. Louis to Milwaukee on September 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Gateway Station
Milwaukee Mitchell MKE AirportCheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.Fastest
Greyhound Lines, Inc. + FlixBus
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.No tags
FlixBus
Gateway Station
Goerke's Corners Park & Ride (Brookfield)No tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
Milwaukee Bus Station, St. Paul & N6th road.No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from St. Louis to Milwaukee.

Bus
Average Price$43 - $213Average Duration14h 14m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$51 - $271Average Duration8h 18m
48kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from St. Louis to Milwaukee

Among the sustainable travel choices, the train stands out as the good way to reach Milwaukee. The journey takes about 8 hours 18 minutes and with fares starting at just $51, it presents an excellent value for a comfortable ride.

8train per day
8h 18mAverage Duration
$51Cheapest ticket
48kgCO₂ emissions

Bus St. Louis to Milwaukee: Trip Overview

Average ticket price$65
Average bus trip duration14h 14m
Number of daily buses11
Earliest bus departure2:00am
Distance327 miles (527 km)
Latest bus departure11:30pm

St. Louis to Milwaukee Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Milwaukee is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from St. Louis to Milwaukee from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from St. Louis to Milwaukee, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip St. Louis - Milwaukee

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/17
$61
09/18
$52
Today
$104
09/20
$54
09/21
$49
09/22
$56
09/23
$37
09/24
$56
busbud logoThe cheapest trip from St. Louis to Milwaukee was searched and found on Sep 23, 2025 with a price of $37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Milwaukee, as early as possible.

You can expect to pay from $37 to $107 for a bus ticket from St. Louis to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-09-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from St. Louis to Milwaukee.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Milwaukee, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Milwaukee that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St. Louis to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from St. Louis to Milwaukee?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Milwaukee to St. Louis

You can also go to Milwaukee by train

Train from St. Louis to Milwaukee

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Buses Connecting St. Louis

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Popular Buses Connecting Milwaukee

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