What is the distance between Siena and Syracuse?

The distance separating Siena and Syracuse is 479 miles (772 km).

What are the departure and arrival stations when taking the bus from Siena to Syracuse?

If you're headed to Syracuse from Siena, chances are that your bus will leave from Piazza Gramsci and arrive at Fermata dell'autobus Siracusa. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are WonderWorks, Everson Museum of Art, NBT Bank Stadium, Onondaga Historical Association Museum and The Great New York State Fair.

Bus Siena to Syracuse from $58 | Refundable Tickets

Previously seen trips

Next departures for Siena to Syracuse on November 12
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:05am	Siena Train Station	20h 35m	8:40pm	Terminal Interbus	No tags
Bus	6:45pm	Siena Train Station	14h 50m	9:35am	Terminal Interbus	No tags
Bus	11:39pm	Siena (Stellino)	21h 1m	8:40pm	Terminal Interbus	No tags
Bus	12:05am	Siena Train Station	20h 35m	8:40pm	Terminal Interbus	No tags
Bus	6:55pm	Siena Train Station	14h 40m	9:35am	Terminal Interbus	No tags

Get from Siena to Syracuse

This route is served by bus only

The journey takes about 14 hours 40 minutes and with fares starting at just $61, it presents an excellent value for a comfortable ride.

1bus per day

14h 40mAverage Duration

480 milesDistance

19kgCO₂ emissions

Compare bus companies

FlixBus

3.5/511,288 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Siena and Syracuse?

Stops in Siena

A - Piazza Gramsci

B - Via Sallustio Bandini, 21

C - Via Giuseppe Mazzini, 58

D - Via Riccardo Lombardi, 42

E - Torre Fiorentina

F - Siena Zona Industriale

Stops in Syracuse

A - Fermata dell'autobus Siracusa

B - Siracusa

C - Siracusa - Terminal Bus (Stazione FS)

Frequently asked questions about traveling from Siena to Syracuse by bus

What is the distance between Siena and Syracuse?
What are the departure and arrival stations when taking the bus from Siena to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/10

No data

11/11

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Today

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11/13

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11/14

$59

11/15

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11/16

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11/17

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The cheapest trip from Siena to Syracuse was searched and found on Nov 14, 2025 with a price of $59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Syracuse, as early as possible.

You can expect to pay from $59 to $59 for a bus ticket from Siena to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-11-14.