Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Rodoviário de Santa Maria | Itajaí Bus Terminal | Cheapest | ||||
| Bus | Terminal Rodoviário de Santa Maria | Itajaí Bus Terminal | Fastest | ||||
| Bus | Terminal Rodoviário de Santa Maria | Itajaí Bus Terminal | No tags | ||||
| Bus | Terminal Rodoviário de Santa Maria | Itajaí Bus Terminal | No tags | ||||
| Bus | Terminal Rodoviário de Santa Maria | Itajaí Bus Terminal | No tags |
Last refresh of the prices: Today at 2:50 AM -03.
Get from Santa Maria to Itajaí
The journey takes about 14 hours 40 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Maria and Itajaí?
Stops in Santa Maria
- A
Terminal Rodoviário de Santa Maria
Rua Pedro Pereira 1450 - lj 101, Santa Maria - RS, 72547-700
Stops in Itajaí
- AAv. Gov. Adolfo Konder, 1583-1705 - Cidade Nova, Itajaí - SC, Brazil
- B
Terminal Rodoviário Internacional de Itajaí
Avenida Governador Adolfo Konder, 1201 - São Vicente, Itajaí - SC 88308-000 - C
Vila Operaria - Itajai
Vila Operária, Rio de Janiero, Brasil
Compare bus companies
Based on 16 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the wifi. União Santa Cruz ticket prices on this trip start at $56
Frequently asked questions about traveling from Santa Maria, RS, BR to Itajaí by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Maria to Itajaí?
The cheapest bus tickets from Santa Maria to Itajaí start from $56. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Maria to Itajaí?
The average bus trip duration from Santa Maria to Itajaí is 14h 40m, covering a distance of 365 miles (588 km). The quickest bus can get you there in 12h 20m and is operated by União Santa Cruz.
Which bus companies service the Santa Maria to Itajaí route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Santa Maria to Itajaí?
The earliest bus departs from Santa Maria to Itajaí at 8:00am. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from Santa Maria to Itajaí?
A bus trip from Santa Maria to Itajaí generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Maria, RS, BR to Itajaí was searched and found on Dec 2, 2025 with a price of $48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, RS, BR to Itajaí, as early as possible.
You can expect to pay from $48 to $82 for a bus ticket from Santa Maria, RS, BR to Itajaí based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-12-02.
Top traveled bus routes
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