Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Chicago 95Th & Dan Ryan | CheapestFastest | ||||
 | Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags | ||||
| Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Yesterday at 2:43 AM EST.
Compare 2 ways to go from Salisbury to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 4 hours 5 minutes and with fares starting at just $124, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Salisbury, NC, US to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Salisbury to Chicago?
The cheapest bus tickets from Salisbury to Chicago start from $124. The average price for this route is around $175. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Salisbury to Chicago?
The average bus trip duration from Salisbury to Chicago is 1d 4h, covering a distance of 577 miles (930 km). The quickest bus can get you there in 22h 45m and is operated by Greyhound.
Which bus companies service the Salisbury to Chicago route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Salisbury to Chicago?
The earliest bus departs from Salisbury to Chicago at 6:15am. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Salisbury to Chicago?
A bus trip from Salisbury to Chicago generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to Chicago was searched and found on Dec 2, 2025 with a price of $154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to Chicago, as early as possible.
What's the cheapest way to go from Salisbury, NC, US to Chicago?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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