Busbud recommends taking the train from Reno to San Diego
Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 20 hours 1 minute and with fares starting at just $139, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5420 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $116
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Reno to San Diego.
We make it our job to connect you with the most dependable bus companies that cover bus service from Reno to San Diego.
Whether it is cheap bus tickets or more luxurious buses going to San Diego from Reno, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Reno and San Diego?
Stops in Reno
A - Reno Station
101169 E Commercial Row, Reno, NV 89501, USAReno Station
B - Reno Tahoe Airport
Howard W. Cannon Terminal, 2001 E Plumb Ln, Reno, NV 89502, USAReno Tahoe Airport
Frequently asked questions for your trip Reno - San Diego, CA, US
How far is Reno from San Diego?
About 493 miles (796 km) separate Reno and San Diego.
What are the departure and arrival stations when taking the bus from Reno to San Diego?
Most of the buses traveling from Reno to San Diego leave from Reno Station and arrive at Mission Valley Sheraton. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are La Jolla Cove, SeaWorld San Diego, Pacific Surf School, Torrey Pines Gliderport and USS Midway Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/22
$108
08/23
$117
Today
$198
08/25
$113
08/26
$93
08/27
$85
08/28
$83
08/29
$133
The cheapest trip from Reno to San Diego, CA, US was searched and found on Aug 28, 2025 with a price of $83
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Reno to San Diego, CA, US, as early as possible.
You can expect to pay from $83 to $198 for a bus ticket from Reno to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $83 which is on 2025-08-28.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Reno to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Reno to San Diego.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Reno to San Diego.
Make a music playlist for your bus ride from Reno to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Reno to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.