Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal O'Higgins Rancagua | Terminal de Buses Santa Cruz | CheapestFastest | |||||
 | Terminal de Buses O'Higgins | Terminal Santa Cruz | No tags | |||||
| Terminal O'Higgins Rancagua | Terminal de Buses Santa Cruz | No tags | |||||
| Terminal de Buses O'Higgins | Terminal Santa Cruz | No tags | |||||
| Terminal O'Higgins Rancagua | Terminal de Buses Santa Cruz | No tags |
Last refresh of the prices: Last Sunday at 4:17 PM -03.
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Bus Rancagua to Santa Cruz, CL: Trip Overview
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Rancagua to Santa Cruz Bus
With Busbud, comparing and booking tickets for a bus from Rancagua to Santa Cruz is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Rancagua to Santa Cruz from the most reliable bus companies operating this trip.
Discover how much the bus trip from Rancagua to Santa Cruz will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Rancagua and Santa Cruz?
Frequently asked questions for your trip Rancagua - Santa Cruz, CL
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rancagua to Santa Cruz, CL was searched and found on Oct 1, 2025 with a price of $4To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rancagua to Santa Cruz, CL, as early as possible.
You can expect to pay from $4 to $6 for a bus ticket from Rancagua to Santa Cruz, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $4 which is on 2025-10-01.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Rancagua to Santa Cruz.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rancagua to Santa Cruz, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rancagua to Santa Cruz will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rancagua to Santa Cruz.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top traveled bus routes
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Popular Buses Connecting Rancagua
Buses Leaving from Rancagua
- Bus from Rancagua to Santiago
- Bus Rancagua - Temuco
- Rancagua - Talca
- Bus from Rancagua to Chillan
- Bus Rancagua - Curico
- Rancagua - Pichilemu
- Bus from Rancagua to Osorno Province
- Bus Rancagua - Pucon
- Rancagua - Valdivia
- Bus from Rancagua to Angol
- Bus Rancagua - Talcahuano
- Rancagua - Villarrica
- Bus from Rancagua to Concepción
- Bus Rancagua - Nacimiento
- Rancagua - Panguipulli
Buses Going to Rancagua
- Bus from Santiago to Rancagua
- Bus Concepción - Rancagua
- Talca - Rancagua
- Bus from Chillan to Rancagua
- Bus Valdivia - Rancagua
- Pichilemu - Rancagua
- Bus from Renaico to Rancagua
- Bus Vina del Mar - Rancagua
- Coronel - Rancagua
- Bus from Curico to Rancagua
- Bus Angol - Rancagua
- Lautaro - Rancagua
- Bus from Freire to Rancagua
- Bus Carahue - Rancagua
- Lanco - Rancagua
Popular Buses Connecting Santa Cruz
Buses Leaving from Santa Cruz
Buses Going to Santa Cruz
Popular routes in this country
- Bus from Santiago to Valparaiso
- Bus Santiago - Pucon
- Valparaiso - Santiago
- Bus from Santiago to Pichilemu
- Bus Puerto Montt - Santiago
- Puerto Montt - Pucon
- Bus from Calama to Santiago
- Bus Puerto Natales - Estancia Pudeto
- Pucon - Puerto Montt
- Bus from Osorno Province to Pucon
- Bus Santiago - Vina del Mar
- Santiago - La Serena
- Bus from Puerto Varas to Pucon
- Bus Concepción - Santiago
- Santiago - Temuco