Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | CheapestFastest | ||||
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags | ||||
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags | ||||
| Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags | ||||
| Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags |
Last refresh of the prices: Yesterday at 10:18 AM -03.
Get from Panguipulli to Santiago
The journey takes about 10 hours and with fares starting at just $13, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panguipulli and Santiago?
Stops in Panguipulli
- A
Terminal de Autobuses de Panguipulli
Diego Portales 269, Panguipulli, Región de los Ríos, Chile - B
Terminal Tur Bus de Panguipulli
José Miguel Carrera 784, Panguipulli, Región de los Ríos, Chile
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Zapadores
Los Zapadores 608, Recoleta, Región Metropolitana, Chile
Compare bus companies
Frequently asked questions about traveling from Panguipulli to Santiago, CL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panguipulli to Santiago?
The cheapest bus tickets from Panguipulli to Santiago start from $13. The average price for this route is around $25. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panguipulli to Santiago?
The average bus trip duration from Panguipulli to Santiago is 10h, covering a distance of 437 miles (704 km). The quickest bus can get you there in 9h 50m and is operated by Nar Bus.
Which bus companies service the Panguipulli to Santiago route?
Several major bus companies operate on this route with 4 buses available per day, including services from buses TranSantin, Nar Bus, Buses Jet Sur.
What is the earliest and latest departure time for the bus from Panguipulli to Santiago?
The earliest bus departs from Panguipulli to Santiago at 8:00pm. And the latest bus departs at 9:20pm.
What are the CO₂ emissions for the bus trip from Panguipulli to Santiago?
A bus trip from Panguipulli to Santiago generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Panguipulli to Santiago?
According to Busbud customers, the highest-rated bus company on this route is buses TranSantin, with an average rating of 4.2 out of 5 stars based on 280 reviews.
Which bus company has the best Wi-Fi from Panguipulli to Santiago?
Based on reviews on Busbud, the bus company Nar Bus has the best Wi-Fi rating with a score of 3.0.
Which bus company has the most timely service from Panguipulli to Santiago?
According to Busbud traveller reviews, the most timely bus company on this route is Buses Jet Sur, with a punctuality rating of 4.4 out of 5 stars.
Which bus company has the cleanest buses from Panguipulli to Santiago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panguipulli to Santiago, CL was searched and found on Dec 6, 2025 with a price of $17To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panguipulli to Santiago, CL, as early as possible.
You can expect to pay from $17 to $48 for a bus ticket from Panguipulli to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $21 which is on 2025-12-11.
Usually Nar Bus, buses TranSantin will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
