Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Greyhound Station | Downtown Greyhound Station | Fastest | ||||
| Bus | Greyhound Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Downtown Greyhound Station | No tags | ||||
| Bus | Greyhound Station | Downtown Greyhound Station | No tags |
Last refresh of the prices: Today at 11:15 AM CST.
Get from Mobile to Chicago
The journey takes about 1 day, 20 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Mobile Chicago recent customer reviews
Bus didnt take me to my final location. Bus dropped me off at the grayhound station and i had to walk to the amtrak station
Tyler H.
Frequently asked questions about traveling from Mobile to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Chicago?
The cheapest bus tickets from Mobile to Chicago start from $99. The average price for this route is around $182. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Chicago?
The average bus trip duration from Mobile to Chicago is 1d , covering a distance of 774 miles (1247 km). The quickest bus can get you there in 23h 20m and is operated by Greyhound.
Which bus companies service the Mobile to Chicago route?
Several major train operators operate on this route with 12 trains available per day.
What is the earliest and latest departure time for the bus from Mobile to Chicago?
The earliest bus departs from Mobile to Chicago at 12:05am. And the latest bus departs at 3:55pm.
What are the CO₂ emissions for the bus trip from Mobile to Chicago?
A bus trip from Mobile to Chicago generates an estimated 31 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Chicago was searched and found on Dec 5, 2025 with a price of $123To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Chicago, as early as possible.
You can expect to pay from $123 to $416 for a bus ticket from Mobile to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $123 which is on 2025-12-05.
