Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mendoza Terminal | Terminal de Buses La Serena | CheapestFastest | ||||
| Bus | Mendoza Terminal | Terminal de Buses La Serena | No tags |
Last refresh of the prices: Today at 2:08 AM -03.
Get from Mendoza to La Serena
The journey takes about 11 hours 45 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mendoza and La Serena?
Stops in Mendoza
- AAv. Gdor. Ricardo Videla, Mendoza, Argentina
- BAv. Gobernador Ricardo Videla , M5519 Mendoza, Argentina
- CAcceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
- DChile 1124, 5500 Mendoza, Argentina
- E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina - F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina
Stops in La Serena
- AAmunátegui 107, La Serena, Región de Coquimbo, Chile
- B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Compare bus companies
Based on 2095 reviews, the company was rated 3.9 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. CATA Internacional ticket prices on this trip start at $68
CATA Internacional Mendoza La Serena recent customer reviews
It would be better if we didn't have to print tickets off to board the bus- this is quite difficult when traveling
Wendy L.
The bus broke down for 5 hours we waited for another one to pick us up. No explanation from the staff (they just laughed). At the terminal once we arrived they had no compensation, no apology nothing ! Terrible journey and won't book that company again .
Rachel H.
Frequently asked questions about traveling from Mendoza, AR to La Serena, CL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mendoza to La Serena?
The cheapest bus tickets from Mendoza to La Serena start from $68. The average price for this route is around $93. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mendoza to La Serena?
The average bus trip duration from Mendoza to La Serena is 11h 45m, covering a distance of 251 miles (404 km). The quickest bus can get you there in 11h 45m and is operated by CATA Internacional.
Which bus companies service the Mendoza to La Serena route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Mendoza to La Serena?
The earliest bus departs from Mendoza to La Serena at 8:15pm. And the latest bus departs at 8:16pm.
What are the CO₂ emissions for the bus trip from Mendoza to La Serena?
A bus trip from Mendoza to La Serena generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mendoza, AR to La Serena, CL was searched and found on Dec 6, 2025 with a price of $64To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza, AR to La Serena, CL, as early as possible.
