What is the distance between Jackson and Indianapolis?

Jackson and Indianapolis are 563 miles (907 km) apart.

What are the departure and arrival stations when taking the bus from Jackson to Indianapolis?

If you're headed to Indianapolis from Jackson, chances are that your bus will depart from Jackson Bus Station and arrive at Greyhound Amtrak Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

Bus Jackson to Indianapolis from $120 | Refundable Tickets

Next bus departures

Next departures for Jackson to Indianapolis on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	12:55pm	Jackson (Union Station)	23h 5m	1:00pm	Downtown Transit Center	Cheapest
	Bus	12:55pm	Jackson (Union Station)	17h 30m	7:25am	Indianapolis Bus Station	Fastest
	Bus	2:00pm	Jackson (Union Station)	21h 5m	12:05pm	Indianapolis Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:30pm	Jackson (Union Station)	1d 1h	7:50pm	Downtown Transit Center	No tags
	Bus	5:30pm	Jackson (Union Station)	22h 5m	4:35pm	Indianapolis Bus Station	No tags

Last refresh of the prices: Last Friday at 5:28 PM CST.

Compare 2 ways to go from Jackson to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 22 hours 5 minutes and with fares starting at just $126, it presents an excellent value for a comfortable ride.

5bus per day

22h 5mAverage Duration

562 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$126 - $259	Average Duration22h 5m	CO₂ emissions 23kg CO₂e
Train	Average Price$190 - $969	Average Duration1d 5h	CO₂ emissions 82kg CO₂e

Where are the popular stops in Jackson and Indianapolis?

Stops in Jackson

A
Jackson Bus Station
300 W Capitol St, Jackson, MS 39201, USA
B
Love's Travel Stop - Jackson
730 US-80, Flowood, MS 39232, USA

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
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Compare bus companies

Greyhound

3.5/587,397 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Jackson, MS, US to Indianapolis by bus

What is the distance between Jackson and Indianapolis?
What are the departure and arrival stations when taking the bus from Jackson to Indianapolis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

$216

11/25

No data

Today

$174

11/27

No data

11/28

$167

11/29

No data

11/30

No data

12/01

$185

The cheapest trip from Jackson, MS, US to Indianapolis was searched and found on Nov 28, 2025 with a price of $167

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jackson, MS, US to Indianapolis, as early as possible.

You can expect to pay from $167 to $266 for a bus ticket from Jackson, MS, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $167 which is on 2025-11-28.