What is the travel distance from Isernia to Rome?

The distance separating Isernia and Rome is 93 miles (150 km).

What are the departure and arrival stations when taking the bus from Isernia to Rome?

The majority of buses traveling from Isernia to Rome start their journey at Isernia and wind up at Rome Tiburtina Bus Station. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Rome?

Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Fontana di Trevi, Spanish Steps, Teatro dell'Opera di Roma, Museo di Roma and Colosseum.

Bus Isernia to Rome from $16 | Refundable Tickets

Previously seen trips

Next departures for Isernia to Rome on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:50pm	Isernia	7h 40m	11:30pm	Rome Anagnina	No tags
Bus	3:50pm	Isernia	7h 5m	10:55pm	Rome Tiburtina Bus Station	No tags
Bus	3:50pm	Isernia	7h 40m	11:30pm	Rome Anagnina	No tags
Bus	3:50pm	Isernia	7h 5m	10:55pm	Rome Tiburtina Bus Station	No tags
Bus	3:50pm	Isernia	7h 40m	11:30pm	Rome Anagnina	No tags

Compare 3 ways to go from Isernia to Rome

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 2 hours and with fares starting at just $11, it presents an excellent value for a comfortable ride.

5carpool per day

2hAverage Duration

93 milesDistance

6kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$20 - $99	Average Duration9h 5m	CO₂ emissions 4kg CO₂e
Train	Average Price$21 - $22	Average Duration5h	CO₂ emissions 4kg CO₂e
Carpool	Average Price$11 - $22	Average Duration2h	CO₂ emissions 6kg CO₂e

Where are the popular stops in Isernia and Rome?

Stops in Isernia

A
Isernia
Piazza della Repubblica, 9, 86170 Isernia IS, Italy
Visit page

Stops in Rome

A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
B
Rome Ciampino Airport
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Compare bus companies

FlixBus

3.5/511,432 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Isernia to Rome by bus

What is the travel distance from Isernia to Rome?
What are the departure and arrival stations when taking the bus from Isernia to Rome?
What are the best sights and things to do in Rome?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

$22

11/23

$52

Today

$16

11/25

$16

11/26

$22

11/27

$19

11/28

$28

11/29

$26

The cheapest trip from Isernia to Rome was searched and found on Nov 24, 2025 with a price of $16

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Rome, as early as possible.

You can expect to pay from $16 to $71 for a bus ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2025-11-25.