Bus Tickets from Indianapolis to San Antonio, US

Next departures

Next departures for Indianapolis to San Antonio on September 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Downtown Transit Center
San Antonio Bus StationCheapest
Greyhound Lines, Inc. + Valley Transit
Indianapolis Bus Station
San Antonio Bus StationFastest
Greyhound Lines, Inc. + Valley Transit
Indianapolis Bus Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Indianapolis Bus Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Pearl DistrictNo tags

Last refresh of the prices: Yesterday at 4:19 PM EDT.

Accepted payments

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Compare 2 ways to go from Indianapolis to San Antonio.

Bus
Average Price$99 - $317Average Duration1d 6h
40kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$151 - $706Average Duration1d 17h
146kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to San Antonio

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 1 day, 6 hours 25 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.

11bus per day
1d 6hAverage Duration
$99Cheapest ticket
40kgCO₂ emissions

Bus Indianapolis to San Antonio, US: Trip Overview

Average ticket price$125
Average bus trip duration1d 6h
Number of daily buses11
Earliest bus departure3:15am
Distance996 miles (1606 km)
Latest bus departure11:30pm

Indianapolis to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to San Antonio.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to San Antonio.

From cheap bus tickets to more luxurious buses traveling from Indianapolis to San Antonio, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Indianapolis - San Antonio, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/26
No data
09/27
$288
Today
No data
09/29
$218
09/30
No data
10/01
No data
10/02
$169
10/03
No data
busbud logoThe cheapest trip from Indianapolis to San Antonio, US was searched and found on Oct 2, 2025 with a price of $169

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Antonio, US, as early as possible.

You can expect to pay from $169 to $508 for a bus ticket from Indianapolis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $169 which is on 2025-10-02.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to San Antonio.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to San Antonio that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Indianapolis to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Indianapolis to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from San Antonio, US to Indianapolis

You can also go to San Antonio, US by train

Train from Indianapolis to San Antonio, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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