Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Framingham Intermodal - 2 Franklin St | Downtown Greyhound Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Framingham Intermodal - 2 Franklin St | 537-517 W. Jackson Blvd | No tags | ||||
| Bus | Framingham Intermodal - 2 Franklin St | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 6:01 AM EST.
Compare 2 ways to go from Framingham to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 9 hours 50 minutes and with fares starting at just $125, it presents an excellent value for a comfortable ride.
Where are the popular stops in Framingham and Chicago?
Stops in Framingham
- A
Framingham Flutie Pass Bus Stop
43 Flutie Pass Commuter Lot (Park and Ride Lot - Routes 9 & 30 - Exit 13 off I-90), Framingham, MA 01701 - B
Shoppers World Bus Stop
1 Worcester Rd, Framingham, MA 01701, USA - C
Route 9 East Park and Ride
1672 Worcester Rd, Framingham, MA 01702, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Framingham to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Framingham to Chicago?
The cheapest bus tickets from Framingham to Chicago start from $125. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Framingham to Chicago?
The average bus trip duration from Framingham to Chicago is 1d 9h, covering a distance of 830 miles (1338 km). The quickest bus can get you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Framingham to Chicago route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the bus from Framingham to Chicago?
The earliest bus departs from Framingham to Chicago at 11:35am. And the latest bus departs at 2:45pm.
What are the CO₂ emissions for the bus trip from Framingham to Chicago?
A bus trip from Framingham to Chicago generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Framingham to Chicago was searched and found on Dec 31, 2025 with a price of $119To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Framingham to Chicago, as early as possible.
What's the cheapest way to go from Framingham to Chicago?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
People from around the world trust Busbud
Popular bus departures from Framingham
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