Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Autostazione Enna - Via Leonardo da Vinci | Rome Tiburtina Bus Station | Cheapest | ||||
| Bus | Autostazione Enna - Via Leonardo da Vinci | Rome Tiburtina Bus Station | Fastest | ||||
| Bus | Autostazione Enna - Via Leonardo da Vinci | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Autostazione Enna - Via Leonardo da Vinci | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Autostazione Enna - Via Leonardo da Vinci | Rome Anagnina | No tags |
Last refresh of the prices: Last Wednesday at 10:58 PM CET.
Compare 2 ways to go from Enna to Rome
Among the sustainable travel choices, the Carpool stands out as a good way to reach Rome. The journey takes about 9 hours 50 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$38 - $128 | Average Duration16h 40m | 12kg CO₂e | ||
Carpool | Average Price$54 - $93 | Average Duration9h 50m | 21kg CO₂e |
Where are the popular stops in Enna and Rome?
Stops in Enna
- A
Enna Bassa fermata dell'autobus
94100 Enna EN, Italy - B
Enna Quadrivio S. Anna
Enna,, Italy - C
Enna - Fermata dell'autobus
A19 Palermo - Catania 118, 94100 Enna EN, Italy
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Enna to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Enna to Rome?
The cheapest bus tickets from Enna to Rome start from $38. The average price for this route is around $70. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Enna to Rome?
The average bus trip duration from Enna to Rome is 16h 40m, covering a distance of 309 miles (498 km). The quickest bus can get you there in 12h 20m and is operated by FlixBus.
Which bus companies service the Enna to Rome route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Enna to Rome?
The earliest bus departs from Enna to Rome at 7:30am. And the latest bus departs at 8:10pm.
What are the CO₂ emissions for the bus trip from Enna to Rome?
A bus trip from Enna to Rome generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Enna to Rome was searched and found on Feb 15, 2026 with a price of $78To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Enna to Rome, as early as possible.
You can expect to pay from $78 to $130 for a bus ticket from Enna to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2026-02-15.
