How much is the bus ticket from Detroit to San Diego?

The cheapest bus tickets from Detroit to San Diego start from $137. The average price for this route is around $381. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Detroit to San Diego?

The average bus trip duration from Detroit to San Diego is 2d 17h, covering a distance of 1961 miles (3163 km). The quickest bus can get you there in 2d 10h and is operated by FlixBus .

Which bus companies service the Detroit to San Diego route?

Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Detroit to San Diego?

The earliest bus departs from Detroit to San Diego at 6:40am. And the latest bus departs at 11:25pm.

What are the CO₂ emissions for the bus trip from Detroit to San Diego?

A bus trip from Detroit to San Diego generates an estimated 79 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Detroit to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from Detroit to San Diego?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Detroit to San Diego?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Detroit to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Detroit to San Diego from $302 | Refundable Tickets

Next bus departures

Next departures for Detroit to San Diego on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	3d 1h	10:15pm	Downtown SD (Seaport)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	7:30pm	Detroit Bus Station	2d 17h	9:40am	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:30pm	Detroit Bus Station	2d 19h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	2d 17h	1:40pm	UCSD Health La Jolla Station	No tags

Next departures for Detroit to San Diego on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15am	Detroit Bus Station	2d 9h	2:10pm	San Diego (Old Town-FlixBus)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	7:15am	Detroit Bus Station	2d 9h	1:40pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:30pm	Detroit Bus Station	2d 19h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	2d 12h	5:35pm	UCSD Health La Jolla Station	No tags

Next departures for Detroit to San Diego on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:15am	Detroit Bus Station	2d 11h	3:55pm	UCSD Health La Jolla Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:15am	Detroit Bus Station	2d 12h	4:25pm	San Diego (Old Town-FlixBus)	No tags
	Bus	7:30pm	Detroit Bus Station	2d 19h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Next departures for Detroit to San Diego on December 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	3d 1h	10:15pm	Downtown SD (Seaport)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	6:40am	Detroit Bus Station	2d 13h	5:35pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	6:40am	Detroit Bus Station	2d 14h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	6:40am	Detroit Bus Station	2d 14h	5:45pm	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:25pm	Detroit Bus Station	2d 17h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Last refresh of the prices: Yesterday at 9:48 PM EST.

Compare 2 ways to go from Detroit to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 2 days, 9 hours 27 minutes and with fares starting at just $307, it presents an excellent value for a comfortable ride.

2train per day

2d 9hAverage Duration

1964 milesDistance

288kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$137 - $572	Average Duration2d 17h	CO₂ emissions 79kg CO₂e
Train	Average Price$307 - $1,908	Average Duration2d 9h	CO₂ emissions 288kg CO₂e

Where are the popular stops in Detroit and San Diego?

Stops in Detroit

A
Detroit Bus Station
1001 Howard St, Detroit, MI 48226, USA
Visit page

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,415 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,527 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Detroit, MI to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Detroit to San Diego?
The cheapest bus tickets from Detroit to San Diego start from $137. The average price for this route is around $381. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to San Diego?
The average bus trip duration from Detroit to San Diego is 2d 17h, covering a distance of 1961 miles (3163 km). The quickest bus can get you there in 2d 10h and is operated by FlixBus.
Which bus companies service the Detroit to San Diego route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Detroit to San Diego?
The earliest bus departs from Detroit to San Diego at 6:40am. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Detroit to San Diego?
A bus trip from Detroit to San Diego generates an estimated 79 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Detroit to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Detroit to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Detroit to San Diego?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Detroit to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/03

$359

12/04

$372

Today

$456

12/06

$590

12/07

No data

12/08

$479

12/09

No data

12/10

$308

The cheapest trip from Detroit, MI to San Diego, CA, US was searched and found on Dec 10, 2025 with a price of $308

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to San Diego, CA, US, as early as possible.

You can expect to pay from $308 to $590 for a bus ticket from Detroit, MI to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $308 which is on 2025-12-10.