Bus Tickets from Chicago to Syracuse, US

Find affordable bus tickets from Chicago to Syracuse, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
SunAug 10
from $130
MonAug 11
from $104
TueAug 12
from $90
WedAug 13
from $90
ThuAug 14
FriAug 15
from $99
SatAug 16
from $99
SunAug 17

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 11 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: August 12 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 11 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: August 12 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 11 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: August 12 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 11 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: August 12 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 11 at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: August 12 at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Chicago to Syracuse.

Average Price$61 - $245Average Duration20h 10m
24kg CO₂e5 out of 5 stars
Most eco-friendly
Average Price$60 - $1,371Average Duration12h 58m
86kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Chicago to Syracuse

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 20 hours 10 minutes and with fares starting at just $61, it presents an excellent value for a comfortable ride.

7bus per day
20h 10mAverage Duration
$61Cheapest ticket
24kgCO₂ emissions

Bus Chicago to Syracuse, US: Trip Overview

Average ticket price$96
Average bus trip duration20h 10m
Number of daily buses7
Earliest bus departure5:25am
Distance591 miles (952 km)
Latest bus departure11:15pm

Chicago to Syracuse Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Syracuse.

We make sure you can find a bus service from Chicago to Syracuse from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Chicago to Syracuse, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Chicago - Syracuse, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/06
$131
08/07
$119
Today
$137
08/09
$131
08/10
$122
08/11
$96
08/12
$82
08/13
$82
busbud logoThe cheapest trip from Chicago to Syracuse, US was searched and found on Aug 12, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Syracuse, US, as early as possible.

You can expect to pay from $82 to $137 for a bus ticket from Chicago to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-08-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Syracuse but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to Syracuse, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Syracuse that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Syracuse while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Chicago to Syracuse, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Chicago to Syracuse, US

You can also go to Syracuse, US by train

Train from Chicago to Syracuse, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse