Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Spartanburg | CheapestFastest | ||||
 | Bus | Downtown Greyhound Station | Spartanburg | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Spartanburg | No tags |
Last refresh of the prices: Yesterday at 8:58 AM CST.
Compare 2 ways to go from Chicago to Spartanburg
Among the sustainable travel choices, the bus stands out as the good way to reach Spartanburg. The journey takes about 1 day, 2 hours 45 minutes and with fares starting at just $110, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Spartanburg?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
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Frequently asked questions about traveling from Chicago to Spartanburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Spartanburg?
The cheapest bus tickets from Chicago to Spartanburg start from $110. The average price for this route is around $172. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Spartanburg?
The average bus trip duration from Chicago to Spartanburg is 1d 2h, covering a distance of 554 miles (894 km). The quickest bus can get you there in 19h 25m and is operated by FlixBus.
Which bus companies service the Chicago to Spartanburg route?
What is the earliest and latest departure time for the bus from Chicago to Spartanburg?
The earliest bus departs from Chicago to Spartanburg at 5:25am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Chicago to Spartanburg?
A bus trip from Chicago to Spartanburg generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Spartanburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Chicago to Spartanburg?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Chicago to Spartanburg?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Spartanburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Spartanburg was searched and found on Dec 1, 2025 with a price of $299To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Spartanburg, as early as possible.
What's the cheapest way to go from Chicago to Spartanburg?
The bus is the cheapest travel choice for this destination
