How much is the bus ticket from Brussels to Prague?

The cheapest bus tickets from Brussels to Prague start from $44. The average price for this route is around $76. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Brussels to Prague?

The average bus trip duration from Brussels to Prague is 19h 15m, covering a distance of 445 miles (718 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet .

Which bus companies service the Brussels to Prague route?

Several major bus companies operate on this route with 28 buses available per day, including services from FlixBus , RegioJet , BlaBlaCar Bus , Musil Tour .

What is the earliest and latest departure time for the bus from Brussels to Prague?

The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 11:35pm.

What are the CO₂ emissions for the bus trip from Brussels to Prague?

A bus trip from Brussels to Prague generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Brussels to Prague?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1057 reviews.

Which bus company has the best Wi-Fi from Brussels to Prague?

Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company has the most timely service from Brussels to Prague?

According to Busbud traveller reviews, the most timely bus company on this route is RegioJet , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Brussels to Prague?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.3 out of 5 stars.

Bus Brussels to Prague from $47 | Refundable Tickets

Next bus departures

Next departures for Brussels to Prague on December 5
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:00pm	Brussels North Train Station	19h 35m	5:35pm	Prague Hradčanská	Cheapest
Bus	8:10pm	Brussels-South (Gare du Midi)	13h 35m	9:45am	Florenc	Fastest
Bus	9:25pm	Brussels North Train Station	15h 15m	12:40pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:15pm	Brussels North Train Station	17h 25m	3:40pm	Prague (Central Bus Station Florenc)	No tags
Bus	10:55pm	Brussels North Train Station	18h 35m	5:30pm	Prague (Main Railway Station)	No tags

Next departures for Brussels to Prague on December 6
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:55am	Brussels North Train Station	16h 5m	3:00am	Prague (Main Station - parking)	Cheapest
Bus	10:30am	Brussels North Train Station	13h 35m	12:05am	Prague (Na Knížecí)	Fastest
Bus	8:00am	Brussels North Train Station	15h 10m	11:10pm	Prague (Central Bus Station Florenc)	No tags
Bus	9:00am	Brussels North Train Station	18h 35m	3:35am	Prague (Central Bus Station Florenc)	No tags
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags

Next departures for Brussels to Prague on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Brussels South (Gare du Midi)	11h 55m	6:25am	Florenc	CheapestFastest

Next departures for Brussels to Prague on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	2:20pm	Brussels-South (Gare du Midi)	19h 25m	9:45am	Florenc	CheapestFastest

Last refresh of the prices: Today at 6:28 PM CET.

Compare 2 ways to go from Brussels to Prague

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.

28bus per day

19h 15mAverage Duration

445 milesDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$44 - $203	Average Duration19h 15m	CO₂ emissions 18kg CO₂e
Train	Average Price$64 - $295	Average Duration14h 36m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Brussels and Prague?

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Stops in Prague

A
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
D
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare bus companies

FlixBus

3.5/511,528 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

RegioJet

4/51,058 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

BlaBlaCar Bus

3.5/511,193 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.6

Musil Tour

CZ bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Brussels to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brussels to Prague?
The cheapest bus tickets from Brussels to Prague start from $44. The average price for this route is around $76. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Prague?
The average bus trip duration from Brussels to Prague is 19h 15m, covering a distance of 445 miles (718 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 28 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus, Musil Tour.
What is the earliest and latest departure time for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 11:35pm.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus trip from Brussels to Prague generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which bus company has the best Wi-Fi from Brussels to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Brussels to Prague?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/03

No data

12/04

$60

Today

$70

12/06

$58

12/07

$60

12/08

$78

12/09

No data

12/10

$47

The cheapest trip from Brussels to Prague was searched and found on Dec 10, 2025 with a price of $47

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.

You can expect to pay from $47 to $190 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-12-10.