Find coaches from Brussels to Prague

Next departures

Next departures from Brussels to Prague on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RegioJet
    		Brussels South (Gare du Midi)
    		FlorencCheapestFastest
    BlaBlaCar Bus
      		Brussels-South (Gare du Midi)
      		FlorencNo tags

      Last refresh of the prices: Today at 4:48 AM CET.

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      Compare 2 ways to travel from Brussels to Prague

      We recommend taking the bus

      Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just US$37, it presents an excellent value for a comfortable ride.

      29bus per day
      19h 15mAverage duration
      729 kmDistance
      18kgCO₂ emissions
      Bus
      		Average priceUS$37 - US$201Average duration19h 15m
      18kg CO₂e
      Train
      		Average priceUS$87 - US$1 035Average duration14h 58m
      17kg CO₂e

      Bus Brussels to Prague: Trip Overview

      Average ticket priceUS$81
      Average bus trip duration19h 15m
      Number of daily buses29
      Earliest bus departure00:45
      Distance729 km
      Latest bus departure23:35

      Brussels to Prague Bus

      Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Brussels to Prague.

      Bus service from Brussels to Prague will be provided by the most trusted bus companies.

      From cheap bus tickets to more luxurious buses travelling from Brussels to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

      Frequently asked questions on the trip Brussels - Prague

      1. How much does a bus ticket from Brussels to Prague cost?

        The bus ticket price from Brussels to Prague starts at US$37. The best way to find cheap bus tickets from Brussels to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from Brussels to Prague?

        The average travel time between Brussels and Prague is around 19h 15m, although the fastest bus will take about 11h 55m. This is the time it takes to travel the 719 km that separates the two cities.

      3. How many daily bus connections are there between Brussels and Prague?

        The number of buses from Brussels to Prague can differ depending on the day of the week. On average, there are 29 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brussels to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from Brussels to Prague?

        When taking the bus from Brussels to Prague, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, RegioJet.

      5. What are the departure and arrival stations when taking the bus from Brussels to Prague?

        Buses travelling between Brussels and Prague leave from Brussels South (Gare du Midi) or Brux-Nord and arrive at PRG Airport, Tomíčkova, Černý Most.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      30/10
      US$60
      31/10
      US$75
      Today
      US$81
      02/11
      US$72
      03/11
      US$69
      04/11
      US$52
      05/11
      No data
      06/11
      US$48
      busbud logoThe cheapest trip from Brussels to Prague was searched and found on 06 Nov 2025 with a price of US$48

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague as early as possible.

      You can expect to pay from US$48 to US$194 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$48, which is on 2025-11-06.

      About Bus Travel

      Bus Travel Tips

      If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Brussels to Prague but it'll also be endearing to native speakers who will surely appreciate your effort.

      Much more than a mere vehicle taking you from Brussels to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

      Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Brussels to Prague that are otherwise impossible to come by with a plane.

      Make a music playlist for your bus ride from Brussels to Prague, and enjoy the scenery to tunes from your own personal soundtrack.

      Did you know?

      9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

      The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

      The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

      What's the cheapest way to go from Brussels to Prague?

      busbud logoThe bus is the cheapest travel choice for this destination

      Will you be returning to Brussels by bus?

      Bus from Prague to Brussels

      You can also go to Prague by train

      Train from Brussels to Prague

      Why choose Busbud?

      The Best Way To Book Bus and Train Tickets

      Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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