Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brindisi Bus Stop | Terminal Bus Palermo | CheapestFastest |
Last refresh of the prices: Yesterday at 4:27 PM CET.
Get from Brindisi to Palermo
The journey takes about 1 day, 1 hour 15 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.
Where are the popular stops in Brindisi and Palermo?
Stops in Brindisi
- AVia Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
- C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Brindisi to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brindisi to Palermo?
The cheapest bus tickets from Brindisi to Palermo start from $47. The average price for this route is around $70. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brindisi to Palermo?
The average bus trip duration from Brindisi to Palermo is 1d 1h, covering a distance of 299 miles (482 km). The quickest bus can get you there in 11h 50m and is operated by FlixBus.
Which bus companies service the Brindisi to Palermo route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Brindisi to Palermo?
The earliest bus departs from Brindisi to Palermo at 12:40pm. And the latest bus departs at 11:10pm.
What are the CO₂ emissions for the bus trip from Brindisi to Palermo?
A bus trip from Brindisi to Palermo generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brindisi to Palermo was searched and found on Apr 2, 2026 with a price of $122To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brindisi to Palermo, as early as possible.
You can expect to pay from $122 to $122 for a bus ticket from Brindisi to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $122 which is on 2026-04-02.
