Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santa Fe Depot | Greyhound Amtrak Station | No tags | |||||
| Old Town San Diego | Greyhound Amtrak Station | No tags | |||||
| Santa Fe Depot | Greyhound Amtrak Station | No tags | |||||
| Old Town San Diego | Greyhound Amtrak Station | No tags | |||||
| Santa Fe Depot | Greyhound Amtrak Station | No tags |
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Compare 2 ways to travel from San Diego to Indianapolis
We recommend taking the busAmong the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 2 days, 6 hours 50 minutes and with fares starting at just US$126, it presents an excellent value for a comfortable ride.
Train San Diego, CA, US to Indianapolis: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5557 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$249
San Diego to Indianapolis Train
Busbud helps you find a train from San Diego to Indianapolis. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make sure you can find a train service from San Diego to Indianapolis from the most reliable train companies operating this trip.
From train tickets to high-end trains trip from San Diego to Indianapolis, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip San Diego, CA, US - Indianapolis
How much does a cheap train ticket from San Diego to Indianapolis cost?
The average train ticket price from San Diego to Indianapolis is US$249. The best way to find cheap train tickets from San Diego to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from San Diego to Indianapolis?
A train trip between San Diego and Indianapolis is around 2d 6h, although the fastest train will take about 2d 6h. This is the time it takes to travel the 2876 km that separates the two cities.
How many daily train are there between San Diego and Indianapolis?
The number of trains from San Diego to Indianapolis can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from San Diego to Indianapolis by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from San Diego to Indianapolis?
When taking the train from San Diego to Indianapolis, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to Indianapolis was searched and found on 29 Oct 2025 with a price of US$338To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to Indianapolis as early as possible.
About Train Travel
Train Travel Tips
There are many train stations in the world, explore station pages on Busbud to get all information you need.
Regional train? High-speed train? Whichever train to Indianapolis you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between San Diego and Indianapolis compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Create your own real-life musical score by curating a personalised train travel playlist – the perfect accompaniment for your journey from San Diego to Indianapolis.
Did you know?
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.
Japanese trains are always on time. It is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologise to each passenger.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
Top Travelled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
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